SCYL3, as a novel binding partner and regulator of ROCK2, promotes hepatocellular carcinoma progression.
Lei MML, Leung CON, Lau EYT, Leung RWH, Ma VWS, Tong M, Lu YY, Huang CY, Zhu QH, Ng IOL, Ma S, Lee TKW.
Lei MML, et al. Among authors: lee tkw.
JHEP Rep. 2022 Oct 13;5(1):100604. doi: 10.1016/j.jhepr.2022.100604. eCollection 2023 Jan.
JHEP Rep. 2022.
PMID: 36440258
Free PMC article.
The functional significance and mechanistic consequences of SCYL3 were examined in SCYL3-knockdown/overexpressing HCC cells. In vivo tumor progression was evaluated in Tp53 (KO)/c-Myc (OE) mice using the sleeping beauty transposon system. Potential downstream pathways were …
The functional significance and mechanistic consequences of SCYL3 were examined in SCYL3-knockdown/overexpressing HCC cells. In vivo tumor p …