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Naturally occurring capsid substitutions render HIV-1 cyclophilin A independent in human cells and TRIM-cyclophilin-resistant in Owl monkey cells.
Chatterji U, Bobardt MD, Stanfield R, Ptak RG, Pallansch LA, Ward PA, Jones MJ, Stoddart CA, Scalfaro P, Dumont JM, Besseghir K, Rosenwirth B, Gallay PA. Chatterji U, et al. Among authors: rosenwirth b. J Biol Chem. 2005 Dec 2;280(48):40293-300. doi: 10.1074/jbc.M506314200. Epub 2005 Sep 30. J Biol Chem. 2005. PMID: 16199531 Free article.
Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent.
Ptak RG, Gallay PA, Jochmans D, Halestrap AP, Ruegg UT, Pallansch LA, Bobardt MD, de Béthune MP, Neyts J, De Clercq E, Dumont JM, Scalfaro P, Besseghir K, Wenger RM, Rosenwirth B. Ptak RG, et al. Among authors: rosenwirth b. Antimicrob Agents Chemother. 2008 Apr;52(4):1302-17. doi: 10.1128/AAC.01324-07. Epub 2008 Jan 22. Antimicrob Agents Chemother. 2008. PMID: 18212100 Free PMC article.