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Antibody activation using DNA-based logic gates.
Janssen BM, van Rosmalen M, van Beek L, Merkx M. Janssen BM, et al. Angew Chem Int Ed Engl. 2015 Feb 16;54(8):2530-3. doi: 10.1002/anie.201410779. Epub 2015 Jan 8. Angew Chem Int Ed Engl. 2015. PMID: 25573528
Enzymatic glycan remodeling-metal free click (GlycoConnect™) provides homogenous antibody-drug conjugates with improved stability and therapeutic index without sequence engineering.
Wijdeven MA, van Geel R, Hoogenboom JH, Verkade JMM, Janssen BMG, Hurkmans I, de Bever L, van Berkel SS, van Delft FL. Wijdeven MA, et al. Among authors: janssen bmg. MAbs. 2022 Jan-Dec;14(1):2078466. doi: 10.1080/19420862.2022.2078466. MAbs. 2022. PMID: 35634725 Free PMC article.
Correction: Verkade, J.M.M.; et al. A Polar Sulfamide Spacer Significantly Enhances the Manufacturability, Stability, and Therapeutic Index of Antibody-Drug Conjugates. Antibodies 2018, 7, 12.
Verkade JMM, Wijdeven MA, Van Geel R, Janssen BMG, Van Berkel SS, Van Delft FL; Antibodies Editorial Office. Verkade JMM, et al. Among authors: janssen bmg. Antibodies (Basel). 2018 Aug 30;7(3):34. doi: 10.3390/antib7030034. Antibodies (Basel). 2018. PMID: 31544884 Free PMC article.