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Page 1
Structural reconstruction of protein ancestry.
Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3897-3902. doi: 10.1073/pnas.1613477114. Epub 2017 Mar 29.
Proc Natl Acad Sci U S A. 2017.
PMID: 28356519
Free PMC article.
Expression of high-affinity human antibody fragments in bacteria.
Rouet R, Lowe D, Dudgeon K, Roome B, Schofield P, Langley D, Andrews J, Whitfeld P, Jermutus L, Christ D.
Rouet R, et al. Among authors: roome b.
Nat Protoc. 2012 Feb 2;7(2):364-73. doi: 10.1038/nprot.2011.448.
Nat Protoc. 2012.
PMID: 22301775
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Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis.
Kass I, Hoke DE, Costa MG, Reboul CF, Porebski BT, Cowieson NP, Leh H, Pennacchietti E, McCoey J, Kleifeld O, Borri Voltattorni C, Langley D, Roome B, Mackay IR, Christ D, Perahia D, Buckle M, Paiardini A, De Biase D, Buckle AM.
Kass I, et al. Among authors: roome b.
Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2524-9. doi: 10.1073/pnas.1403182111. Epub 2014 Jun 9.
Proc Natl Acad Sci U S A. 2014.
PMID: 24927554
Free PMC article.
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Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.
Sabouri Z, Schofield P, Horikawa K, Spierings E, Kipling D, Randall KL, Langley D, Roome B, Vazquez-Lombardi R, Rouet R, Hermes J, Chan TD, Brink R, Dunn-Walters DK, Christ D, Goodnow CC.
Sabouri Z, et al. Among authors: roome b.
Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2567-75. doi: 10.1073/pnas.1406974111. Epub 2014 May 12.
Proc Natl Acad Sci U S A. 2014.
PMID: 24821781
Free PMC article.
Clinical Trial.
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Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis.
Allen MD, Christie M, Jones P, Porebski BT, Roome B, Freund SM, Buckle AM, Bycroft M, Christ D.
Allen MD, et al. Among authors: roome b.
Protein Eng Des Sel. 2015 Oct;28(10):445-50. doi: 10.1093/protein/gzv021. Epub 2015 Apr 15.
Protein Eng Des Sel. 2015.
PMID: 25877662
Free PMC article.
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