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Page 1
Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice.
Chew TW, Jiang X, Yan J, Wang W, Lusa AL, Carrier BJ, West AA, Malysheva OV, Brenna JT, Gregory JF 3rd, Caudill MA. Chew TW, et al. Among authors: carrier bj. J Nutr. 2011 Aug;141(8):1475-81. doi: 10.3945/jn.111.138859. Epub 2011 Jun 22. J Nutr. 2011. PMID: 21697299 Free PMC article.
Genetic Variation in Choline-Metabolizing Enzymes Alters Choline Metabolism in Young Women Consuming Choline Intakes Meeting Current Recommendations.
Ganz AB, Cohen VV, Swersky CC, Stover J, Vitiello GA, Lovesky J, Chuang JC, Shields K, Fomin VG, Lopez YS, Mohan S, Ganti A, Carrier B, Malysheva OV, Caudill MA. Ganz AB, et al. Among authors: carrier b. Int J Mol Sci. 2017 Jan 26;18(2):252. doi: 10.3390/ijms18020252. Int J Mol Sci. 2017. PMID: 28134761 Free PMC article.
Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis.
Ganz AB, Shields K, Fomin VG, Lopez YS, Mohan S, Lovesky J, Chuang JC, Ganti A, Carrier B, Yan J, Taeswuan S, Cohen VV, Swersky CC, Stover JA, Vitiello GA, Malysheva OV, Mudrak E, Caudill MA. Ganz AB, et al. Among authors: carrier b. FASEB J. 2016 Oct;30(10):3321-3333. doi: 10.1096/fj.201500138RR. Epub 2016 Jun 24. FASEB J. 2016. PMID: 27342765 Free PMC article. Clinical Trial.