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Leukemia stem cells and human acute lymphoblastic leukemia.
Bernt KM, Armstrong SA. Bernt KM, et al. Semin Hematol. 2009 Jan;46(1):33-8. doi: 10.1053/j.seminhematol.2008.09.010. Semin Hematol. 2009. PMID: 19100366 Free PMC article. Review.
The fact that most anticancer therapy is directed against the bulk of the tumor, and possibly spares the cancer stem cells, may lie at the heart of treatment failures with conventional modalities. ...
The fact that most anticancer therapy is directed against the bulk of the tumor, and possibly spares the cancer stem cells, may lie a …
Exome first approach to reduce diagnostic costs and time - retrospective analysis of 111 individuals with rare neurodevelopmental disorders.
Klau J, Abou Jamra R, Radtke M, Oppermann H, Lemke JR, Beblo S, Popp B. Klau J, et al. Eur J Hum Genet. 2022 Jan;30(1):117-125. doi: 10.1038/s41431-021-00981-z. Epub 2021 Oct 25. Eur J Hum Genet. 2022. PMID: 34690354 Free PMC article.
On average, the total potentially savable costs in our study amount to 3,025.56 per individual. Cost savings by first tier exome sequencing lie primarily in genetic, metabolic, and cMRI testing in this German cohort, underscoring the utility of performing exome sequencing …
On average, the total potentially savable costs in our study amount to 3,025.56 per individual. Cost savings by first tier exome sequencing …