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2017 2
2019 2
2020 1
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2022 3
2024 0

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Page 1
Development of a First-in-Class Small-Molecule Inhibitor of the C-Terminal Hsp90 Dimerization.
Bhatia S, Spanier L, Bickel D, Dienstbier N, Woloschin V, Vogt M, Pols H, Lungerich B, Reiners J, Aghaallaei N, Diedrich D, Frieg B, Schliehe-Diecks J, Bopp B, Lang F, Gopalswamy M, Loschwitz J, Bajohgli B, Skokowa J, Borkhardt A, Hauer J, Hansen FK, Smits SHJ, Jose J, Gohlke H, Kurz T. Bhatia S, et al. Among authors: lungerich b. ACS Cent Sci. 2022 May 25;8(5):636-655. doi: 10.1021/acscentsci.2c00013. Epub 2022 Apr 27. ACS Cent Sci. 2022. PMID: 35647282 Free PMC article.
3-Hydroxy-propanamidines, a New Class of Orally Active Antimalarials Targeting Plasmodium falciparum.
Knaab TC, Held J, Burckhardt BB, Rubiano K, Okombo J, Yeo T, Mok S, Uhlemann AC, Lungerich B, Fischli C, Pessanha de Carvalho L, Mordmüller B, Wittlin S, Fidock DA, Kurz T. Knaab TC, et al. Among authors: lungerich b. J Med Chem. 2021 Mar 25;64(6):3035-3047. doi: 10.1021/acs.jmedchem.0c01744. Epub 2021 Mar 5. J Med Chem. 2021. PMID: 33666415 Free PMC article.
Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity.
Lienau C, Gräwert T, Alves Avelar LA, Illarionov B, Held J, Knaab TC, Lungerich B, van Geelen L, Meier D, Geissler S, Cynis H, Riederer U, Buchholz M, Kalscheuer R, Bacher A, Mordmüller B, Fischer M, Kurz T. Lienau C, et al. Among authors: lungerich b. Eur J Med Chem. 2019 Nov 1;181:111555. doi: 10.1016/j.ejmech.2019.07.058. Epub 2019 Jul 22. Eur J Med Chem. 2019. PMID: 31382119
Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed ortho-C(sp2)-H-Hydroxylation.
Berger A, Knak T, Kiffe-Delf AL, Mudrovcic K, Singh V, Njoroge M, Burckhardt BB, Gopalswamy M, Lungerich B, Ackermann L, Gohlke H, Chibale K, Kalscheuer R, Kurz T. Berger A, et al. Among authors: lungerich b. Pharmaceuticals (Basel). 2022 Aug 10;15(8):984. doi: 10.3390/ph15080984. Pharmaceuticals (Basel). 2022. PMID: 36015133 Free PMC article.
Assessing the Anthelmintic Candidates BLK127 and HBK4 for Their Efficacy on Haemonchus contortus Adults and Eggs, and Their Hepatotoxicity and Biotransformation.
Zajíčková M, Prchal L, Vokřál I, Nguyen LT, Kurz T, Gasser R, Bednářová K, Mičundová M, Lungerich B, Michel O, Skálová L. Zajíčková M, et al. Among authors: lungerich b. Pharmaceutics. 2022 Mar 30;14(4):754. doi: 10.3390/pharmaceutics14040754. Pharmaceutics. 2022. PMID: 35456588 Free PMC article.
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.
Leven M, Knaab TC, Held J, Duffy S, Meister S, Fischli C, Meitzner D, Lehmann U, Lungerich B, Kuna K, Stahlke P, Delves MJ, Buchholz M, Winzeler EA, Avery VM, Mordmüller B, Wittlin S, Kurz T. Leven M, et al. Among authors: lungerich b. J Med Chem. 2017 Jul 27;60(14):6036-6044. doi: 10.1021/acs.jmedchem.7b00140. Epub 2017 Jul 17. J Med Chem. 2017. PMID: 28653845
Inhibition of the Yersinia pestis Methylerythritol Phosphate Pathway of Isoprenoid Biosynthesis by α-Phenyl-Substituted Reverse Fosmidomycin Analogues.
Ball HS, Girma M, Zainab M, Riley H, Behrendt CT, Lienau C, Konzuch S, Avelar LAA, Lungerich B, Soojhawon I, Noble SM, Kurz T, Couch RD. Ball HS, et al. Among authors: lungerich b. ACS Omega. 2020 Mar 4;5(10):5170-5175. doi: 10.1021/acsomega.9b04171. eCollection 2020 Mar 17. ACS Omega. 2020. PMID: 32201804 Free PMC article.
Phenotypic screening of the 'Kurz-box' of chemicals identifies two compounds (BLK127 and HBK4) with anthelmintic activity in vitro against parasitic larval stages of Haemonchus contortus.
Nguyen LT, Kurz T, Preston S, Brueckmann H, Lungerich B, Herath HMPD, Koehler AV, Wang T, Skálová L, Jabbar A, Gasser RB. Nguyen LT, et al. Among authors: lungerich b. Parasit Vectors. 2019 Apr 30;12(1):191. doi: 10.1186/s13071-019-3426-7. Parasit Vectors. 2019. PMID: 31039802 Free PMC article.