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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation.
Gélinas R, Mailleux F, Dontaine J, Bultot L, Demeulder B, Ginion A, Daskalopoulos EP, Esfahani H, Dubois-Deruy E, Lauzier B, Gauthier C, Olson AK, Bouchard B, Des Rosiers C, Viollet B, Sakamoto K, Balligand JL, Vanoverschelde JL, Beauloye C, Horman S, Bertrand L. Gélinas R, et al. Among authors: demeulder b. Nat Commun. 2018 Jan 25;9(1):374. doi: 10.1038/s41467-017-02795-4. Nat Commun. 2018. PMID: 29371602 Free PMC article.
Differential regulation of eEF2 and p70S6K by AMPKalpha2 in heart.
Demeulder B, Zarrinpashneh E, Ginion A, Viollet B, Hue L, Rider MH, Vanoverschelde JL, Beauloye C, Horman S, Bertrand L. Demeulder B, et al. Biochim Biophys Acta. 2013 Jun;1832(6):780-90. doi: 10.1016/j.bbadis.2013.02.015. Epub 2013 Mar 4. Biochim Biophys Acta. 2013. PMID: 23466593 Free article.
Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation.
Sanchez Canedo C, Demeulder B, Ginion A, Bayascas JR, Balligand JL, Alessi DR, Vanoverschelde JL, Beauloye C, Hue L, Bertrand L. Sanchez Canedo C, et al. Among authors: demeulder b. Am J Physiol Endocrinol Metab. 2010 Apr;298(4):E761-9. doi: 10.1152/ajpendo.00421.2009. Epub 2010 Jan 5. Am J Physiol Endocrinol Metab. 2010. PMID: 20051528 Free article.