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A new mouse model of Ehlers-Danlos syndrome generated using CRISPR/Cas9-mediated genomic editing.
Nitahara-Kasahara Y, Mizumoto S, Inoue YU, Saka S, Posadas-Herrera G, Nakamura-Takahashi A, Takahashi Y, Hashimoto A, Konishi K, Miyata S, Masuda C, Matsumoto E, Maruoka Y, Yoshizawa T, Tanase T, Inoue T, Yamada S, Nomura Y, Takeda S, Watanabe A, Kosho T, Okada T. Nitahara-Kasahara Y, et al. Among authors: hashimoto a. Dis Model Mech. 2021 Dec 1;14(12):dmm048963. doi: 10.1242/dmm.048963. Epub 2021 Dec 23. Dis Model Mech. 2021. PMID: 34850861 Free PMC article.
Systematic investigation of the skin in Chst14-/- mice: A model for skin fragility in musculocontractural Ehlers-Danlos syndrome caused by CHST14 variants (mcEDS-CHST14).
Hirose T, Mizumoto S, Hashimoto A, Takahashi Y, Yoshizawa T, Nitahara-Kasahara Y, Takahashi N, Nakayama J, Takehana K, Okada T, Nomura Y, Yamada S, Kosho T, Watanabe T. Hirose T, et al. Among authors: hashimoto a. Glycobiology. 2021 Feb 9;31(2):137-150. doi: 10.1093/glycob/cwaa058. Glycobiology. 2021. PMID: 32601684
Giant Cavernous Hemangioma of the Adrenal Gland in an Elderly Patient.
Hashimoto A, Yoshino H, Yoshikawa F, Kumashiro N, Ando Y, Yamabe F, Akishima-Fukasawa Y, Honma N, Uchino H, Hirose T. Hashimoto A, et al. Intern Med. 2018 May 1;57(9):1317-1319. doi: 10.2169/internalmedicine.9711-17. Epub 2017 Dec 27. Intern Med. 2018. PMID: 29279502 Free PMC article.
Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with mcEDS-CHST14.
Hirose T, Takahashi N, Tangkawattana P, Minaguchi J, Mizumoto S, Yamada S, Miyake N, Hayashi S, Hatamochi A, Nakayama J, Yamaguchi T, Hashimoto A, Nomura Y, Takehana K, Kosho T, Watanabe T. Hirose T, et al. Among authors: hashimoto a. Biochim Biophys Acta Gen Subj. 2019 Mar;1863(3):623-631. doi: 10.1016/j.bbagen.2018.12.006. Epub 2018 Dec 13. Biochim Biophys Acta Gen Subj. 2019. PMID: 30553867