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Small benzothiazole molecule induces apoptosis and prevents metastasis through DNA interaction and c-MYC gene supression in diffuse-type gastric adenocarcinoma cell line.
Chem Biol Interact. 2018 Oct 1;294:118-127. doi: 10.1016/j.cbi.2018.08.006. Epub 2018 Aug 11.
Chem Biol Interact. 2018.
PMID: 30107152
Our results showed promising anticancer activity against gastric cancer cells ACP-02 (IC(50) = 1.0 muM) and mild activity against other cell lines including non-malignant gastric cell MNP-01 (IC(50) = 3.4 muM). This compound significantly induced S phase cell cycle arrest, …
Our results showed promising anticancer activity against gastric cancer cells ACP-02 (IC(50) = 1.0 muM) and mild activity against other cell …
Inhibitory effect of pisosterol on human glioblastoma cell lines with C-MYC amplification.
Pereira EL, Lima PD, Khayat AS, Bahia MO, Bezerra FS, Andrade-Neto M, Montenegro RC, Pessoa C, Costa-Lotufo LV, Moraes MO, Yoshioka FK, Pinto GR, Burbano RR.
Pereira EL, et al.
J Appl Toxicol. 2011 Aug;31(6):554-60. doi: 10.1002/jat.1596. Epub 2010 Nov 9.
J Appl Toxicol. 2011.
PMID: 21061448
Using fluorescence in situ hybridization analysis with a locus-specific probe for C-MYC showed that 72% of U343 and 65% of AHOL1 cells contained more than two alleles of C-MYC before treatment. ...However, at 1.8 g ml-1 of pisosterol, only 33% of U343 cells and 15% …
Using fluorescence in situ hybridization analysis with a locus-specific probe for C-MYC showed that 72% of U343 and 65% of AHOL1 cell …
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Influence of the palm tree species on the variability of Rhodnius nasutus Stål, 1859 (Hemiptera, Reduviidae, Triatominae).
Dias FB, Paula AS, Belisário CJ, Lorenzo MG, Bezerra CM, Harry M, Diotaiuti L.
Dias FB, et al.
Infect Genet Evol. 2011 Jul;11(5):869-77. doi: 10.1016/j.meegid.2011.02.008. Epub 2011 Feb 16.
Infect Genet Evol. 2011.
PMID: 21335104
The morphometric studies of the F1 generation demonstrated that insects from the babacu (A. speciosa) were significantly larger (p = 0.000) than those collected in carnauba (C. prunifera) palm trees. Also, microsatellite analysis demonstrated a high genetic differentiation …
The morphometric studies of the F1 generation demonstrated that insects from the babacu (A. speciosa) were significantly larger (p = 0.000) …
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First isolation of Cryptococcus gattii molecular type VGII and Cryptococcus neoformans molecular type VNI from environmental sources in the city of Belém, Pará, Brazil.
Costa Sdo P, Lazéra Mdos S, Santos WR, Morales BP, Bezerra CC, Nishikawa MM, Barbosa GG, Trilles L, Nascimento JL, Wanke B.
Costa Sdo P, et al.
Mem Inst Oswaldo Cruz. 2009 Jul;104(4):662-4. doi: 10.1590/s0074-02762009000400023.
Mem Inst Oswaldo Cruz. 2009.
PMID: 19722095
Free article.
Preliminary analysis of 11 environmental samples from the city of Belem showed two positive locations, including a hollow of a kassod tree (Senna siamea) colonized simultaneously by C. gattii molecular type VGII and C. neoformans molecular type VNI, and a birdcage i …
Preliminary analysis of 11 environmental samples from the city of Belem showed two positive locations, including a hollow of a kassod tree ( …
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