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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2004 1
2006 1
2007 2
2008 3
2009 2
2011 1
2012 1
2015 2
2016 2
2017 2
2018 1
2019 5
2020 7
2021 4
2022 3
2023 6
2024 0

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41 results

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Page 1
Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets.
Ohta A, Tanada M, Shinohara S, Morita Y, Nakano K, Yamagishi Y, Takano R, Kariyuki S, Iida T, Matsuo A, Ozeki K, Emura T, Sakurai Y, Takano K, Higashida A, Kojima M, Muraoka T, Takeyama R, Kato T, Kimura K, Ogawa K, Ohara K, Tanaka S, Kikuchi Y, Hisada N, Hayashi R, Nishimura Y, Nomura K, Tachibana T, Irie M, Kawada H, Torizawa T, Murao N, Kotake T, Tanaka M, Ishikawa S, Miyake T, Tamiya M, Arai M, Chiyoda A, Akai S, Sase H, Kuramoto S, Ito T, Shiraishi T, Kojima T, Iikura H. Ohta A, et al. J Am Chem Soc. 2023 Nov 8;145(44):24035-24051. doi: 10.1021/jacs.3c07145. Epub 2023 Oct 24. J Am Chem Soc. 2023. PMID: 37874670
Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor.
Tanada M, Tamiya M, Matsuo A, Chiyoda A, Takano K, Ito T, Irie M, Kotake T, Takeyama R, Kawada H, Hayashi R, Ishikawa S, Nomura K, Furuichi N, Morita Y, Kage M, Hashimoto S, Nii K, Sase H, Ohara K, Ohta A, Kuramoto S, Nishimura Y, Iikura H, Shiraishi T. Tanada M, et al. Among authors: ohta a. J Am Chem Soc. 2023 Aug 2;145(30):16610-16620. doi: 10.1021/jacs.3c03886. Epub 2023 Jul 18. J Am Chem Soc. 2023. PMID: 37463267
Using a GPU to accelerate die and mold fabrication.
Inui M, Ohta A. Inui M, et al. Among authors: ohta a. IEEE Comput Graph Appl. 2007 Jan-Feb;27(1):82-8. doi: 10.1109/mcg.2007.23. IEEE Comput Graph Appl. 2007. PMID: 17220128 Review. No abstract available.
Diverse backbone-cyclized peptides via codon reprogramming.
Kawakami T, Ohta A, Ohuchi M, Ashigai H, Murakami H, Suga H. Kawakami T, et al. Among authors: ohta a. Nat Chem Biol. 2009 Dec;5(12):888-90. doi: 10.1038/nchembio.259. Epub 2009 Oct 25. Nat Chem Biol. 2009. PMID: 19915537
Genome analyses reveal the hybrid origin of the staple crop white Guinea yam (Dioscorea rotundata).
Sugihara Y, Darkwa K, Yaegashi H, Natsume S, Shimizu M, Abe A, Hirabuchi A, Ito K, Oikawa K, Tamiru-Oli M, Ohta A, Matsumoto R, Agre P, De Koeyer D, Pachakkil B, Yamanaka S, Muranaka S, Takagi H, White B, Asiedu R, Innan H, Asfaw A, Adebola P, Terauchi R. Sugihara Y, et al. Among authors: ohta a. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):31987-31992. doi: 10.1073/pnas.2015830117. Epub 2020 Dec 2. Proc Natl Acad Sci U S A. 2020. PMID: 33268496 Free PMC article.
41 results