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In vitro and computational investigations of novel synthetic carboxamide-linked pyridopyrrolopyrimidines with potent activity as SARS-CoV-2-MPro inhibitors.
Aljuhani A, Ahmed HEA, Ihmaid SK, Omar AM, Althagfan SS, Alahmadi YM, Ahmad I, Patel H, Ahmed S, Almikhlafi MA, El-Agrody AM, Zayed MF, Turkistani SA, Abulkhair SH, Almaghrabi M, Salama SA, Al-Karmalawy AA, Abulkhair HS. Aljuhani A, et al. RSC Adv. 2022 Sep 22;12(41):26895-26907. doi: 10.1039/d2ra04015h. eCollection 2022 Sep 16. RSC Adv. 2022. PMID: 36320844 Free PMC article.
Design and Synthesis of Benzene Homologues Tethered with 1,2,4-Triazole and 1,3,4-Thiadiazole Motifs Revealing Dual MCF-7/HepG2 Cytotoxic Activity with Prominent Selectivity via Histone Demethylase LSD1 Inhibitory Effect.
Alsehli M, Aljuhani A, Ihmaid SK, El-Messery SM, Othman DIA, El-Sayed AAA, Ahmed HEA, Rezki N, Aouad MR. Alsehli M, et al. Among authors: aljuhani a. Int J Mol Sci. 2022 Aug 8;23(15):8796. doi: 10.3390/ijms23158796. Int J Mol Sci. 2022. PMID: 35955929 Free PMC article.
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