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RAS in pancreatic cancer.
Lanfredini S, Thapa A, O'Neill E. Lanfredini S, et al. Among authors: thapa a. Biochem Soc Trans. 2019 Aug 30;47(4):961-972. doi: 10.1042/BST20170521. Epub 2019 Jul 24. Biochem Soc Trans. 2019. PMID: 31341034 Review.
TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.
Eyres M, Lanfredini S, Xu H, Burns A, Blake A, Willenbrock F, Goldin R, Hughes D, Hughes S, Thapa A, Vavoulis D, Hubert A, D'Costa Z, Sabbagh A, Abraham AG, Blancher C, Jones S, Verrill C, Silva M, Soonawalla Z, Maughan T, Schuh A, Mukherjee S, O'Neill E. Eyres M, et al. Among authors: thapa a. Gastroenterology. 2021 Aug;161(2):653-668.e16. doi: 10.1053/j.gastro.2021.04.044. Epub 2021 Apr 27. Gastroenterology. 2021. PMID: 33915173
RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.
Papaspyropoulos A, Bradley L, Thapa A, Leung CY, Toskas K, Koennig D, Pefani DE, Raso C, Grou C, Hamilton G, Vlahov N, Grawenda A, Haider S, Chauhan J, Buti L, Kanapin A, Lu X, Buffa F, Dianov G, von Kriegsheim A, Matallanas D, Samsonova A, Zernicka-Goetz M, O'Neill E. Papaspyropoulos A, et al. Among authors: thapa a. Nat Commun. 2018 Jan 30;9(1):424. doi: 10.1038/s41467-017-02786-5. Nat Commun. 2018. PMID: 29382819 Free PMC article.