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DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma.
Yagolovich AV, Isakova AA, Artykov AA, Vorontsova YV, Mazur DV, Antipova NV, Pavlyukov MS, Shakhparonov MI, Gileva AM, Markvicheva EA, Plotnikova EA, Pankratov AA, Kirpichnikov MP, Gasparian ME, Dolgikh DA. Yagolovich AV, et al. Among authors: artykov aa. Int J Mol Sci. 2022 Oct 21;23(20):12687. doi: 10.3390/ijms232012687. Int J Mol Sci. 2022. PMID: 36293545 Free PMC article.
Genetically Modified DR5-Specific TRAIL Variant DR5-B Revealed Dual Antitumor and Protumoral Effect in Colon Cancer Xenografts and an Improved Pharmacokinetic Profile.
Yagolovich AV, Artykov AA, Karmakova TA, Vorontsova MS, Pankratov AA, Andreev-Andrievsky AA, Dolgikh DA, Kirpichnikov MP, Gasparian ME. Yagolovich AV, et al. Among authors: artykov aa. Transl Oncol. 2020 Apr;13(4):100762. doi: 10.1016/j.tranon.2020.100762. Epub 2020 Mar 27. Transl Oncol. 2020. PMID: 32224450 Free PMC article.
Dual targeting of DR5 and VEGFR2 molecular pathways by multivalent fusion protein significantly suppresses tumor growth and angiogenesis.
Isakova AA, Artykov AA, Plotnikova EA, Trunova GV, Khokhlova VА, Pankratov AA, Shuvalova ML, Mazur DV, Antipova NV, Shakhparonov MI, Dolgikh DA, Kirpichnikov MP, Gasparian ME, Yagolovich AV. Isakova AA, et al. Among authors: artykov aa. Int J Biol Macromol. 2024 Jan;255:128096. doi: 10.1016/j.ijbiomac.2023.128096. Epub 2023 Nov 14. Int J Biol Macromol. 2024. PMID: 37972835