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Page 1
The Crossroad of Ion Channels and Calmodulin in Disease.
Urrutia J, Aguado A, Muguruza-Montero A, Núñez E, Malo C, Casis O, Villarroel A. Urrutia J, et al. Among authors: muguruza montero a. Int J Mol Sci. 2019 Jan 18;20(2):400. doi: 10.3390/ijms20020400. Int J Mol Sci. 2019. PMID: 30669290 Free PMC article. Review.
Redox regulation of KV7 channels through EF3 hand of calmodulin.
Nuñez E, Jones F, Muguruza-Montero A, Urrutia J, Aguado A, Malo C, Bernardo-Seisdedos G, Domene C, Millet O, Gamper N, Villarroel A. Nuñez E, et al. Among authors: muguruza montero a. Elife. 2023 Feb 20;12:e81961. doi: 10.7554/eLife.81961. Elife. 2023. PMID: 36803414 Free PMC article.
Do calmodulin binding IQ motifs have built-in capping domains?
Muguruza-Montero A, Ramis R, Nuñez E, R Ballesteros O, G Ibarluzea M, Araujo A, M-Alicante S, Urrutia J, Leonardo A, Bergara A, Villarroel A. Muguruza-Montero A, et al. Protein Sci. 2021 Oct;30(10):2029-2041. doi: 10.1002/pro.4170. Epub 2021 Sep 1. Protein Sci. 2021. PMID: 34392571 Free PMC article. Review.
Atomistic Insights of Calmodulin Gating of Complete Ion Channels.
Núñez E, Muguruza-Montero A, Villarroel A. Núñez E, et al. Among authors: muguruza montero a. Int J Mol Sci. 2020 Feb 14;21(4):1285. doi: 10.3390/ijms21041285. Int J Mol Sci. 2020. PMID: 32075037 Free PMC article. Review.
N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect.
Espejo-Román JM, Rubio-Ruiz B, Chayah-Ghaddab M, Vega-Gutierrez C, García-García G, Muguruza-Montero A, Domene C, Sánchez-Martín RM, Cruz-López O, Conejo-García A. Espejo-Román JM, et al. Among authors: muguruza montero a. Eur J Med Chem. 2023 Oct 5;258:115570. doi: 10.1016/j.ejmech.2023.115570. Epub 2023 Jun 26. Eur J Med Chem. 2023. PMID: 37413883 Free article.
An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel.
Urrutia J, Aguado A, Gomis-Perez C, Muguruza-Montero A, Ballesteros OR, Zhang J, Nuñez E, Malo C, Chung HJ, Leonardo A, Bergara A, Villarroel A. Urrutia J, et al. Among authors: muguruza montero a. BMC Biol. 2021 May 21;19(1):109. doi: 10.1186/s12915-021-01040-1. BMC Biol. 2021. PMID: 34020651 Free PMC article.
MLe-KCNQ2: An Artificial Intelligence Model for the Prognosis of Missense KCNQ2 Gene Variants.
Saez-Matia A, Ibarluzea MG, M-Alicante S, Muguruza-Montero A, Nuñez E, Ramis R, Ballesteros OR, Lasa-Goicuria D, Fons C, Gallego M, Casis O, Leonardo A, Bergara A, Villarroel A. Saez-Matia A, et al. Among authors: muguruza montero a. Int J Mol Sci. 2024 Mar 2;25(5):2910. doi: 10.3390/ijms25052910. Int J Mol Sci. 2024. PMID: 38474157 Free PMC article.
Identification of Riluzole derivatives as novel calmodulin inhibitors with neuroprotective activity by a joint synthesis, biosensor, and computational guided strategy.
Baltasar-Marchueta M, Llona L, M-Alicante S, Barbolla I, Ibarluzea MG, Ramis R, Salomon AM, Fundora B, Araujo A, Muguruza-Montero A, Nuñez E, Pérez-Olea S, Villanueva C, Leonardo A, Arrasate S, Sotomayor N, Villarroel A, Bergara A, Lete E, González-Díaz H. Baltasar-Marchueta M, et al. Among authors: muguruza montero a. Biomed Pharmacother. 2024 Apr 17;174:116602. doi: 10.1016/j.biopha.2024.116602. Online ahead of print. Biomed Pharmacother. 2024. PMID: 38636396