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New Genetic Bomb Trigger: Design, Synthesis, Molecular Dynamics Simulation, and Biological Evaluation of Novel BIBR1532-Related Analogs Targeting Telomerase against Non-Small Cell Lung Cancer.
Pharmaceuticals (Basel). 2022 Apr 14;15(4):481. doi: 10.3390/ph15040481.
Pharmaceuticals (Basel). 2022.
PMID: 35455478
Free PMC article.
Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo Evaluations.
Al-Karmalawy AA, Nafie MS, Shaldam MA, Elmaaty AA, Antar SA, El-Hamaky AA, Saleh MA, Elkamhawy A, Tawfik HO.
Al-Karmalawy AA, et al. Among authors: el hamaky aa.
J Med Chem. 2023 Jan 12;66(1):777-792. doi: 10.1021/acs.jmedchem.2c01668. Epub 2022 Dec 16.
J Med Chem. 2023.
PMID: 36525642
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