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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 3
2004 5
2005 13
2006 10
2007 3
2008 7
2009 6
2010 4
2011 6
2012 6
2013 9
2014 13
2015 9
2016 7
2017 8
2018 5
2019 12
2020 11
2021 20
2022 19
2023 20
2024 15

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189 results

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Page 1
First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure.
Zwirner S, Abu Rmilah AA, Klotz S, Pfaffenroth B, Kloevekorn P, Moschopoulou AA, Schuette S, Haag M, Selig R, Li K, Zhou W, Nelson E, Poso A, Chen H, Amiot B, Jia Y, Minshew A, Michalak G, Cui W, Rist E, Longerich T, Jung B, Felgendreff P, Trompak O, Premsrirut PK, Gries K, Muerdter TE, Heinkele G, Wuestefeld T, Shapiro D, Weissbach M, Koenigsrainer A, Sipos B, Ab E, Zacarias MO, Theisgen S, Gruenheit N, Biskup S, Schwab M, Albrecht W, Laufer S, Nyberg S, Zender L. Zwirner S, et al. Among authors: poso a. Cell. 2024 Mar 28;187(7):1666-1684.e26. doi: 10.1016/j.cell.2024.02.023. Epub 2024 Mar 14. Cell. 2024. PMID: 38490194 Free PMC article. Clinical Trial.
Virus structure and structure-based antivirals.
Plavec Z, Pöhner I, Poso A, Butcher SJ. Plavec Z, et al. Among authors: poso a. Curr Opin Virol. 2021 Dec;51:16-24. doi: 10.1016/j.coviro.2021.09.005. Epub 2021 Sep 24. Curr Opin Virol. 2021. PMID: 34564030 Free PMC article. Review.
Transcription and Translation Inhibitors in Cancer Treatment.
Laham-Karam N, Pinto GP, Poso A, Kokkonen P. Laham-Karam N, et al. Among authors: poso a. Front Chem. 2020 Apr 21;8:276. doi: 10.3389/fchem.2020.00276. eCollection 2020. Front Chem. 2020. PMID: 32373584 Free PMC article. Review.
LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer.
Rudalska R, Harbig J, Snaebjornsson MT, Klotz S, Zwirner S, Taranets L, Heinzmann F, Kronenberger T, Forster M, Cui W, D'Artista L, Einig E, Hinterleitner M, Schmitz W, Dylawerska A, Kang TW, Poso A, Rosenfeldt MT, Malek NP, Bitzer M, Laufer S, Pichler BJ, Popov N, Schulze A, Zender L, Dauch D. Rudalska R, et al. Among authors: poso a. Nat Cancer. 2021 Feb;2(2):201-217. doi: 10.1038/s43018-020-00168-3. Epub 2021 Feb 15. Nat Cancer. 2021. PMID: 35122079
Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells.
Deen AJ, Adinolfi S, Härkönen J, Patinen T, Liu X, Laitinen T, Takabe P, Kainulainen K, Pasonen-Seppänen S, Gawriyski LM, Arasu UT, Selvarajan I, Mäkinen P, Laitinen H, Kansanen E, Kaikkonen MU, Poso A, Varjosalo M, Levonen AL. Deen AJ, et al. Among authors: poso a. Redox Biol. 2024 Feb;69:103031. doi: 10.1016/j.redox.2024.103031. Epub 2024 Jan 4. Redox Biol. 2024. PMID: 38184997 Free PMC article.
Cyclophilin A is a ligand for RAGE in thrombo-inflammation.
Seizer P, von Ungern-Sternberg SNI, Haug V, Dicenta V, Rosa A, Butt E, Nöthel M, Rohlfing AK, Sigle M, Nawroth PP, Nussbaum C, Sperandio M, Kusch C, Meub M, Sauer M, Münzer P, Bieber K, Stanger A, Mack AF, Huber R, Brand K, Lehners M, Feil R, Poso A, Krutzke K, Schäffer TE, Nieswandt B, Borst O, May AE, Zernecke A, Gawaz M, Heinzmann D. Seizer P, et al. Among authors: poso a. Cardiovasc Res. 2024 Mar 30;120(4):385-402. doi: 10.1093/cvr/cvad189. Cardiovasc Res. 2024. PMID: 38175781
Shifting the selectivity of pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily.
Rak M, Tesch R, Berger LM, Shevchenko E, Raab M, Tjaden A, Zhubi R, Balourdas DI, Joerger AC, Poso A, Krämer A, Elson L, Lučić A, Kronenberger T, Hanke T, Strebhardt K, Sanhaji M, Knapp S. Rak M, et al. Among authors: poso a. Eur J Med Chem. 2023 Jun 5;254:115347. doi: 10.1016/j.ejmech.2023.115347. Epub 2023 Apr 7. Eur J Med Chem. 2023. PMID: 37094449
189 results