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Discovery of 5-Methylthiazole-Thiazolidinone Conjugates as Potential Anti-Inflammatory Agents: Molecular Target Identification and In Silico Studies.
Haroun M, Petrou A, Tratrat C, Kolokotroni A, Fesatidou M, Zagaliotis P, Gavalas A, Venugopala KN, Sreeharsha N, Nair AB, Elsewedy HS, Geronikaki A. Haroun M, et al. Among authors: gavalas a. Molecules. 2022 Nov 22;27(23):8137. doi: 10.3390/molecules27238137. Molecules. 2022. PMID: 36500230 Free PMC article.
Potent, orally available, selective COX-2 inhibitors based on 2-imidazoline core.
Sarnpitak P, Mujumdar P, Morisseau C, Hwang SH, Hammock B, Iurchenko V, Zozulya S, Gavalas A, Geronikaki A, Ivanenkov Y, Krasavin M. Sarnpitak P, et al. Among authors: gavalas a. Eur J Med Chem. 2014 Sep 12;84:160-72. doi: 10.1016/j.ejmech.2014.07.023. Epub 2014 Jul 8. Eur J Med Chem. 2014. PMID: 25016374
Identification of Novel Cyclooxygenase-1 Selective Inhibitors of Thiadiazole-Based Scaffold as Potent Anti-Inflammatory Agents with Safety Gastric and Cytotoxic Profile.
Haroun M, Fesatidou M, Petrou A, Tratrat C, Zagaliotis P, Gavalas A, Venugopala KN, Kochkar H, Emeka PM, Younis NS, Elmaghraby DA, Almostafa MM, Chohan MS, Vizirianakis IS, Papadimitriou-Tsantarliotou A, Geronikaki A. Haroun M, et al. Among authors: gavalas a. Molecules. 2023 Apr 12;28(8):3416. doi: 10.3390/molecules28083416. Molecules. 2023. PMID: 37110650 Free PMC article.