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Darolutamide added to docetaxel augments antitumor effect in models of prostate cancer through cell cycle arrest at the G1-S transition.
Buck SAJ, Van Hemelryk A, de Ridder C, Stuurman D, Erkens-Schulze S, Van 't Geloof S, Teubel WJ, Koolen SLW, Martens-Uzunova ES, van Royen ME, de Wit R, Mathijssen RHJ, van Weerden WM. Buck SAJ, et al. Among authors: van hemelryk a. Mol Cancer Ther. 2023 Nov 30. doi: 10.1158/1535-7163.MCT-23-0420. Online ahead of print. Mol Cancer Ther. 2023. PMID: 38030379
Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sustained Androgen Receptor Signaling.
Van Hemelryk A, Tomljanovic I, de Ridder CMA, Stuurman DC, Teubel WJ, Erkens-Schulze S, Verhoef EI, Remmers S, Mahes AJ, van Leenders GJLH, van Royen ME, van de Werken HJG, Grudniewska M, Jenster GW, van Weerden WM. Van Hemelryk A, et al. Cells. 2022 Nov 16;11(22):3632. doi: 10.3390/cells11223632. Cells. 2022. PMID: 36429059 Free PMC article.
The Outcome for Patients With Pathologic Node-Positive Prostate Cancer Treated With Intensity Modulated Radiation Therapy and Androgen Deprivation Therapy: A Case-Matched Analysis of pN1 and pN0 Patients.
Van Hemelryk A, De Meerleer G, Ost P, Poelaert F, De Gersem W, Decaestecker K, De Visschere P, Fonteyne V. Van Hemelryk A, et al. Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2):323-332. doi: 10.1016/j.ijrobp.2016.06.011. Epub 2016 Jun 16. Int J Radiat Oncol Biol Phys. 2016. PMID: 27598803 Clinical Trial.