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Page 1
Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped.
Diabetologia. 2023 Apr;66(4):709-723. doi: 10.1007/s00125-022-05842-y. Epub 2022 Dec 2.
Diabetologia. 2023.
PMID: 36459178
Disruption of Beta-Cell Mitochondrial Networks by the Orphan Nuclear Receptor Nor1/Nr4a3.
Close AF, Dadheech N, Lemieux H, Wang Q, Buteau J.
Close AF, et al.
Cells. 2020 Jan 9;9(1):168. doi: 10.3390/cells9010168.
Cells. 2020.
PMID: 31936632
Free PMC article.
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The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass.
Close AF, Dadheech N, Villela BS, Rouillard C, Buteau J.
Close AF, et al.
J Biol Chem. 2019 Mar 29;294(13):4889-4897. doi: 10.1074/jbc.RA118.005135. Epub 2019 Jan 29.
J Biol Chem. 2019.
PMID: 30696767
Free PMC article.
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The lack of functional nicotinamide nucleotide transhydrogenase only moderately contributes to the impairment of glucose tolerance and glucose-stimulated insulin secretion in C57BL/6J vs C57BL/6N mice.
Close AF, Chae H, Jonas JC.
Close AF, et al.
Diabetologia. 2021 Nov;64(11):2550-2561. doi: 10.1007/s00125-021-05548-7. Epub 2021 Aug 27.
Diabetologia. 2021.
PMID: 34448880
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A critical role for the neural zinc factor ST18 in pancreatic β-cell apoptosis.
Henry C, Close AF, Buteau J.
Henry C, et al. Among authors: close af.
J Biol Chem. 2014 Mar 21;289(12):8413-9. doi: 10.1074/jbc.M114.554915. Epub 2014 Feb 7.
J Biol Chem. 2014.
PMID: 24509857
Free PMC article.
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Protective antioxidant and antiapoptotic effects of ZnCl2 in rat pancreatic islets cultured in low and high glucose concentrations.
Duprez J, Roma LP, Close AF, Jonas JC.
Duprez J, et al. Among authors: close af.
PLoS One. 2012;7(10):e46831. doi: 10.1371/journal.pone.0046831. Epub 2012 Oct 3.
PLoS One. 2012.
PMID: 23056475
Free PMC article.
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