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Viruses traverse the human proteome through peptide interfaces that can be biomimetically leveraged for drug discovery.
Meyniel-Schicklin L, Amaudrut J, Mallinjoud P, Guillier F, Mangeot PE, Lines L, Aublin-Gex A, Scholtes C, Punginelli C, Joly S, Vasseur F, Manet E, Gruffat H, Henry T, Halitim F, Paparin JL, Machin P, Darteil R, Sampson D, Mikaelian I, Lane L, Navratil V, Golinelli-Cohen MP, Terzi F, André P, Lotteau V, Vonderscher J, Meldrum EC, de Chassey B. Meyniel-Schicklin L, et al. Among authors: aublin gex a. Proc Natl Acad Sci U S A. 2024 Jan 30;121(5):e2308776121. doi: 10.1073/pnas.2308776121. Epub 2024 Jan 22. Proc Natl Acad Sci U S A. 2024. PMID: 38252831 Free PMC article.
The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication.
de Chassey B, Aublin-Gex A, Ruggieri A, Meyniel-Schicklin L, Pradezynski F, Davoust N, Chantier T, Tafforeau L, Mangeot PE, Ciancia C, Perrin-Cocon L, Bartenschlager R, André P, Lotteau V. de Chassey B, et al. Among authors: aublin gex a. PLoS Pathog. 2013;9(7):e1003440. doi: 10.1371/journal.ppat.1003440. Epub 2013 Jul 4. PLoS Pathog. 2013. PMID: 23853584 Free PMC article.