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A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl.
Triller G, Vlachou EP, Hashemi H, van Straaten M, Zeelen JP, Kelemen Y, Baehr C, Marker CL, Ruf S, Svirina A, Chandra M, Urban K, Gkeka A, Kruse S, Baumann A, Miller AK, Bartel M, Pravetoni M, Stebbins CE, Papavasiliou FN, Verdi JP. Triller G, et al. Among authors: svirina a. Cell Rep. 2023 Feb 28;42(2):112049. doi: 10.1016/j.celrep.2023.112049. Epub 2023 Jan 30. Cell Rep. 2023. PMID: 36719797 Free PMC article.
Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor.
Eliseev IE, Yudenko AN, Vysochinskaya VV, Svirina AA, Evstratyeva AV, Drozhzhachih MS, Krendeleva EA, Vladimirova AK, Nemankin TA, Ekimova VM, Ulitin AB, Lomovskaya MI, Yakovlev PA, Bukatin AS, Knyazev NA, Moiseenko FV, Chakchir OB. Eliseev IE, et al. Among authors: svirina aa. F1000Res. 2018 Jan 16;7:57. doi: 10.12688/f1000research.13612.2. eCollection 2018. F1000Res. 2018. PMID: 30430004 Free PMC article.