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Page 1
Chirality: a key parameter in chemical probes.
McGown A, Nafie J, Otayfah M, Hassell-Hart S, Tizzard GJ, Coles SJ, Banks R, Marsh GP, Maple HJ, Kostakis GE, Proietti Silvestri I, Colbon P, Spencer J. McGown A, et al. RSC Chem Biol. 2023 Aug 8;4(10):716-721. doi: 10.1039/d3cb00082f. eCollection 2023 Oct 4. RSC Chem Biol. 2023. PMID: 37799583 Free PMC article.
Synthesis and Study of Multifunctional Cyclodextrin-Deferasirox Hybrids.
Gascon JM, Oliveri V, McGown A, Kaya E, Chen YL, Austin C, Walker M, Platt FM, Vecchio G, Spencer J. Gascon JM, et al. Among authors: mcgown a. ChemMedChem. 2019 Aug 20;14(16):1484-1492. doi: 10.1002/cmdc.201900334. Epub 2019 Jun 24. ChemMedChem. 2019. PMID: 31162826 Free PMC article.
Salpyran: A Cu(II) Selective Chelator with Therapeutic Potential.
Devonport J, Bodnár N, McGown A, Bukar Maina M, Serpell LC, Kállay C, Spencer J, Kostakis GE. Devonport J, et al. Among authors: mcgown a. Inorg Chem. 2021 Oct 18;60(20):15310-15320. doi: 10.1021/acs.inorgchem.1c01912. Epub 2021 Oct 5. Inorg Chem. 2021. PMID: 34609139
A Convenient, Rapid, Conventional Heating Route to MIDA Boronates.
McGown A, Edmonds AK, Guest D, Holmes VL, Dadswell C, González-Méndez R, Goodall CAI, Bagley MC, Greenland BW, Spencer J. McGown A, et al. Molecules. 2022 Aug 9;27(16):5052. doi: 10.3390/molecules27165052. Molecules. 2022. PMID: 36014293 Free PMC article.
Solvent-Free Synthesis of Core-Functionalised Naphthalene Diimides by Using a Vibratory Ball Mill: Suzuki, Sonogashira and Buchwald-Hartwig Reactions.
Panther LA, Guest DP, McGown A, Emerit H, Tareque RK, Jose A, Dadswell CM, Coles SJ, Tizzard GJ, González-Méndez R, Goodall CAI, Bagley MC, Spencer J, Greenland BW. Panther LA, et al. Among authors: mcgown a. Chemistry. 2022 Sep 1;28(49):e202201444. doi: 10.1002/chem.202201444. Epub 2022 Jul 13. Chemistry. 2022. PMID: 35621283 Free PMC article.
Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PLpro.
Gil-Moles M, Türck S, Basu U, Pettenuzzo A, Bhattacharya S, Rajan A, Ma X, Büssing R, Wölker J, Burmeister H, Hoffmeister H, Schneeberg P, Prause A, Lippmann P, Kusi-Nimarko J, Hassell-Hart S, McGown A, Guest D, Lin Y, Notaro A, Vinck R, Karges J, Cariou K, Peng K, Qin X, Wang X, Skiba J, Szczupak Ł, Kowalski K, Schatzschneider U, Hemmert C, Gornitzka H, Milaeva ER, Nazarov AA, Gasser G, Spencer J, Ronconi L, Kortz U, Cinatl J, Bojkova D, Ott I. Gil-Moles M, et al. Among authors: mcgown a. Chemistry. 2021 Dec 20;27(71):17928-17940. doi: 10.1002/chem.202103258. Epub 2021 Nov 23. Chemistry. 2021. PMID: 34714566 Free PMC article.