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Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress.
Peyman M, Barroso E, Turcu AL, Estrany F Jr, Smith D, Jurado-Aguilar J, Rada P, Morisseau C, Hammock BD, Valverde ÁM, Palomer X, Galdeano C, Vázquez S, Vázquez-Carrera M. Peyman M, et al. Among authors: turcu al. Biomed Pharmacother. 2023 Dec;168:115667. doi: 10.1016/j.biopha.2023.115667. Epub 2023 Oct 10. Biomed Pharmacother. 2023. PMID: 37826940 Free article.
Inhibition of NMDA receptors through a membrane-to-channel path.
Wilcox MR, Nigam A, Glasgow NG, Narangoda C, Phillips MB, Patel DS, Mesbahi-Vasey S, Turcu AL, Vázquez S, Kurnikova MG, Johnson JW. Wilcox MR, et al. Among authors: turcu al. Nat Commun. 2022 Jul 15;13(1):4114. doi: 10.1038/s41467-022-31817-z. Nat Commun. 2022. PMID: 35840593 Free PMC article.
A Study of the Activity of Adamantyl Amines against Mutant Influenza A M2 Channels Identified a Polycyclic Cage Amine Triple Blocker, Explored by Molecular Dynamics Simulations and Solid-State NMR.
Stampolaki Μ, Hoffmann A, Tekwani K, Georgiou K, Tzitzoglaki C, Ma C, Becker S, Schmerer P, Döring K, Stylianakis I, Turcu AL, Wang J, Vázquez S, Andreas LB, Schmidtke M, Kolocouris A. Stampolaki Μ, et al. Among authors: turcu al. ChemMedChem. 2023 Aug 15;18(16):e202300182. doi: 10.1002/cmdc.202300182. Epub 2023 Jul 25. ChemMedChem. 2023. PMID: 37377066
13 results