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Year Number of Results
1987 2
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Page 1
Showing results for andrea domain
Search for Andrea Domán instead (3 results)
Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway.
Evavold CL, Hafner-Bratkovič I, Devant P, D'Andrea JM, Ngwa EM, Boršić E, Doench JG, LaFleur MW, Sharpe AH, Thiagarajah JR, Kagan JC. Evavold CL, et al. Cell. 2021 Aug 19;184(17):4495-4511.e19. doi: 10.1016/j.cell.2021.06.028. Epub 2021 Jul 21. Cell. 2021. PMID: 34289345 Free PMC article.
Upon cleavage by inflammasome-associated caspases, the N-terminal domain of GSDMD forms membrane pores that promote cytolysis. Numerous proteins promote GSDMD cleavage, but none are known to be required for pore formation after GSDMD cleavage. ...
Upon cleavage by inflammasome-associated caspases, the N-terminal domain of GSDMD forms membrane pores that promote cytolysis. Numero …
Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells.
Rigau M, Ostrouska S, Fulford TS, Johnson DN, Woods K, Ruan Z, McWilliam HEG, Hudson C, Tutuka C, Wheatley AK, Kent SJ, Villadangos JA, Pal B, Kurts C, Simmonds J, Pelzing M, Nash AD, Hammet A, Verhagen AM, Vairo G, Maraskovsky E, Panousis C, Gherardin NA, Cebon J, Godfrey DI, Behren A, Uldrich AP. Rigau M, et al. Science. 2020 Feb 7;367(6478):eaay5516. doi: 10.1126/science.aay5516. Epub 2020 Jan 9. Science. 2020. PMID: 31919129
Furthermore, binding of a second ligand, possibly BTN3A1, to a separate TCR domain incorporating Vdelta2 is also required. This distinctive mode of Ag-dependent T cell activation advances our understanding of diseases involving pAg recognition and creates opportunities for …
Furthermore, binding of a second ligand, possibly BTN3A1, to a separate TCR domain incorporating Vdelta2 is also required. This disti …
Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.
Mengwasser KE, Adeyemi RO, Leng Y, Choi MY, Clairmont C, D'Andrea AD, Elledge SJ. Mengwasser KE, et al. Mol Cell. 2019 Mar 7;73(5):885-899.e6. doi: 10.1016/j.molcel.2018.12.008. Epub 2019 Jan 24. Mol Cell. 2019. PMID: 30686591 Free PMC article.
BRCA2-deficient cells require the apurinic endonuclease activity and the PCNA-binding domain of Ape2 (APEX2), but not Ape1 (APEX1). Furthermore, BRCA2-deficient cells require the 5' flap endonuclease but not the 5'-3' exonuclease activity of Fen1, and chemically inhibiting …
BRCA2-deficient cells require the apurinic endonuclease activity and the PCNA-binding domain of Ape2 (APEX2), but not Ape1 (APEX1). F …
'Dusty core disease' (DuCD): expanding morphological spectrum of RYR1 recessive myopathies.
Garibaldi M, Rendu J, Brocard J, Lacene E, Fauré J, Brochier G, Beuvin M, Labasse C, Madelaine A, Malfatti E, Bevilacqua JA, Lubieniecki F, Monges S, Taratuto AL, Laporte J, Marty I, Antonini G, Romero NB. Garibaldi M, et al. Acta Neuropathol Commun. 2019 Jan 5;7(1):3. doi: 10.1186/s40478-018-0655-5. Acta Neuropathol Commun. 2019. PMID: 30611313 Free PMC article.
DuCD group was associated to an earlier disease onset, a more severe clinical phenotype and a lowest level of RyR1 expression in muscle, compared to the other groups. Variants located in the bridge solenoid and the pore domains were more frequent in DuCD patients. In concl …
DuCD group was associated to an earlier disease onset, a more severe clinical phenotype and a lowest level of RyR1 expression in muscle, com …
[Mediastinal Tumors].
Rückert JC, Elsner A, Andreas MN. Rückert JC, et al. Zentralbl Chir. 2022 Feb;147(1):99-120. doi: 10.1055/a-1674-0693. Epub 2022 Mar 2. Zentralbl Chir. 2022. PMID: 35235970 German.
The middle mediastinal compartment is the most frequent place of mediastinal cystic tumours, whereas the posterior mediastinum is the domain of neurogenic tumours. For selected cases a tissue biopsy is required. ...
The middle mediastinal compartment is the most frequent place of mediastinal cystic tumours, whereas the posterior mediastinum is the dom …
Eating Disorders: the Role of Childhood Trauma and the Emotion Dysregulation.
Brustenghi F, Mezzetti FAF, Di Sarno C, Giulietti C, Moretti P, Tortorella A. Brustenghi F, et al. Psychiatr Danub. 2019 Sep;31(Suppl 3):509-511. Psychiatr Danub. 2019. PMID: 31488781 Free article.
RESULTS: People with eating disorders showed higher average scores, and therefore greater severity than the control group, in all the domains explored, both considering traumatic experiences and emotional dysregulation. The domain emotional neglect showed the closes …
RESULTS: People with eating disorders showed higher average scores, and therefore greater severity than the control group, in all the dom …
Targeting Polymerase Theta (POLθ) for Cancer Therapy.
Patterson-Fortin J, D'Andrea AD. Patterson-Fortin J, et al. Cancer Treat Res. 2023;186:285-298. doi: 10.1007/978-3-031-30065-3_15. Cancer Treat Res. 2023. PMID: 37978141 Review.
Polymerase theta (POLteta) is the critical multi-domain enzyme in microhomology-mediated end-joining DNA double-stranded break repair. ...Development of POLteta inhibitors is an active area of investigation with inhibitors of the N-terminal helicase domain or the C- …
Polymerase theta (POLteta) is the critical multi-domain enzyme in microhomology-mediated end-joining DNA double-stranded break repair …
The Evolution of Rhythm Processing.
Kotz SA, Ravignani A, Fitch WT. Kotz SA, et al. Trends Cogn Sci. 2018 Oct;22(10):896-910. doi: 10.1016/j.tics.2018.08.002. Trends Cogn Sci. 2018. PMID: 30266149 Free article. Review.
A comparative approach can further our understanding of the evolution of rhythm processing by identifying behavioral and neural similarities and differences across cognitive domains and across animal species. We provide an overview of research into rhythm cognition in musi …
A comparative approach can further our understanding of the evolution of rhythm processing by identifying behavioral and neural similarities …
Oxytocin and Social Cognition.
Ebert A, Brüne M. Ebert A, et al. Curr Top Behav Neurosci. 2018;35:375-388. doi: 10.1007/7854_2017_21. Curr Top Behav Neurosci. 2018. PMID: 29019100 Review.
Oxytocin has been linked to many domains within the realm of "social cognition." For example, research has shown that oxytocin affects trusting behavior, cooperation, as well as the perception and processing of facial expressions. ...
Oxytocin has been linked to many domains within the realm of "social cognition." For example, research has shown that oxytocin affect …
1,334 results