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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 1
2004 1
2005 1
2006 1
2008 3
2009 3
2010 1
2011 1
2012 4
2013 7
2014 2
2015 1
2016 1
2018 1
2019 2
2020 3
2021 1
2022 1
2023 1
2024 0

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36 results

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Page 1
Optimizing DMPK Properties: Experiences from a Big Pharma DMPK Department.
Sohlenius-Sternbeck AK, Janson J, Bylund J, Baranczewski P, Breitholtz-Emanuelsson A, Hu Y, Tsoi C, Lindgren A, Gissberg O, Bueters T, Briem S, Juric S, Johansson J, Bergh M, Hoogstraate J. Sohlenius-Sternbeck AK, et al. Among authors: lindgren a. Curr Drug Metab. 2016;17(3):253-70. doi: 10.2174/1389200217666151210125637. Curr Drug Metab. 2016. PMID: 26651977 Review.
Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis.
Flentie K, Harrison GA, Tükenmez H, Livny J, Good JAD, Sarkar S, Zhu DX, Kinsella RL, Weiss LA, Solomon SD, Schene ME, Hansen MR, Cairns AG, Kulén M, Wixe T, Lindgren AEG, Chorell E, Bengtsson C, Krishnan KS, Hultgren SJ, Larsson C, Almqvist F, Stallings CL. Flentie K, et al. Among authors: lindgren aeg. Proc Natl Acad Sci U S A. 2019 May 21;116(21):10510-10517. doi: 10.1073/pnas.1818009116. Epub 2019 May 6. Proc Natl Acad Sci U S A. 2019. PMID: 31061116 Free PMC article.
Towards small molecule inhibitors of mono-ADP-ribosyltransferases.
Ekblad T, Lindgren AE, Andersson CD, Caraballo R, Thorsell AG, Karlberg T, Spjut S, Linusson A, Schüler H, Elofsson M. Ekblad T, et al. Among authors: lindgren ae. Eur J Med Chem. 2015 May 5;95:546-51. doi: 10.1016/j.ejmech.2015.03.067. Epub 2015 Apr 1. Eur J Med Chem. 2015. PMID: 25847771 Free article.
Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics.
Nye TM, Tükenmez H, Singh P, Flores-Mireles AL, Obernuefemann CLP, Pinkner JS, Sarkar S, Bonde M, Lindgren AEG, Dodson KW, Johansson J, Almqvist F, Caparon MG, Hultgren SJ. Nye TM, et al. Among authors: lindgren aeg. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2210912119. doi: 10.1073/pnas.2210912119. Epub 2022 Oct 17. Proc Natl Acad Sci U S A. 2022. PMID: 36252016 Free PMC article.
THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates.
Reithuber E, Wixe T, Ludwig KC, Müller A, Uvell H, Grein F, Lindgren AEG, Muschiol S, Nannapaneni P, Eriksson A, Schneider T, Normark S, Henriques-Normark B, Almqvist F, Mellroth P. Reithuber E, et al. Among authors: lindgren aeg. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2108244118. doi: 10.1073/pnas.2108244118. Proc Natl Acad Sci U S A. 2021. PMID: 34785593 Free PMC article.
PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.
Lindgren AE, Karlberg T, Thorsell AG, Hesse M, Spjut S, Ekblad T, Andersson CD, Pinto AF, Weigelt J, Hottiger MO, Linusson A, Elofsson M, Schüler H. Lindgren AE, et al. ACS Chem Biol. 2013 Aug 16;8(8):1698-703. doi: 10.1021/cb4002014. Epub 2013 Jun 25. ACS Chem Biol. 2013. PMID: 23742272
36 results