Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1947 1
1951 1
1952 5
1955 1
1957 2
1958 1
1962 1
1964 4
1965 3
1966 5
1968 6
1969 14
1970 7
1971 4
1972 9
1973 8
1974 12
1975 11
1976 7
1977 4
1978 3
1979 9
1980 3
1981 8
1982 4
1983 12
1984 8
1985 23
1986 9
1987 7
1988 6
1989 12
1990 10
1991 10
1992 11
1993 5
1994 3
1995 10
1996 6
1997 7
1998 9
1999 9
2000 9
2001 7
2002 7
2003 17
2004 17
2005 12
2006 10
2007 15
2008 12
2009 23
2010 15
2011 19
2012 19
2013 17
2014 26
2015 19
2016 20
2017 16
2018 17
2019 24
2020 18
2021 22
2022 13
2023 8
2024 3

Text availability

Article attribute

Article type

Publication date

Search Results

632 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for anatomy zak
Search for Anatoly Zak instead (1 results)
Targeted inhibition of ZAK ameliorates renal interstitial fibrosis.
Shu S, Liu H, Yang J, Tang H, Li H, Liu Z, Zhou M, Zhu F, Hu Z, Ding K, Lu X, Nie J. Shu S, et al. Transl Res. 2022 Aug;246:49-65. doi: 10.1016/j.trsl.2022.03.002. Epub 2022 Mar 8. Transl Res. 2022. PMID: 35276386
The role of ZAK in kidney disease remains largely unknown. In this study, we systematically investigated the expression and function of ZAK in the progression of tubulointerstitial fibrosis (TIF). ...Whereas, silencing endogenous ZAK ameliorated the amount of …
The role of ZAK in kidney disease remains largely unknown. In this study, we systematically investigated the expression and function …
ZAK Gene Expression in Patients with Helicobacter pylori Infection.
Khani D, Hedayati MA, Nasseri S, Sheikhesmaeili F, Ghadiany R. Khani D, et al. J Gastrointest Cancer. 2022 Jun;53(2):326-332. doi: 10.1007/s12029-021-00611-3. Epub 2021 Feb 23. J Gastrointest Cancer. 2022. PMID: 33620708

BACKGROUND: ZAK protein is a member of the MLK family proteins defined as mediators in the cell cycle. ...The gastric antral biopsy samples with H. pylori vacA s1m2 genotype infection showed a weak correlation with ZAK gene overexpression (p < .1). CONCLUSION:

…
BACKGROUND: ZAK protein is a member of the MLK family proteins defined as mediators in the cell cycle. ...The gastric antral biopsy s …
A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response.
Jandhyala DM, Wong J, Mantis NJ, Magun BE, Leong JM, Thorpe CM. Jandhyala DM, et al. Toxins (Basel). 2016 Sep 2;8(9):259. doi: 10.3390/toxins8090259. Toxins (Basel). 2016. PMID: 27598200 Free PMC article.
We had a novel zak-/- mouse generated to study the role of ZAK signaling in vivo during ricin intoxication. ...Furthermore, compared with zak+/+ mice, zak-/- mice have decreased duodenal damage following in vivo ricin challenge. zak-/- mice demo …
We had a novel zak-/- mouse generated to study the role of ZAK signaling in vivo during ricin intoxication. ...Furthermore, co …
Neuroeconomics.
Zak PJ. Zak PJ. Philos Trans R Soc Lond B Biol Sci. 2004 Nov 29;359(1451):1737-48. doi: 10.1098/rstb.2004.1544. Philos Trans R Soc Lond B Biol Sci. 2004. PMID: 15590614 Free PMC article. Review.
ERbeta targets ZAK and attenuates cellular hypertrophy via SUMO-1 modification in H9c2 cells.
Pai P, Shibu MA, Chang RL, Yang JJ, Su CC, Lai CH, Liao HE, Viswanadha VP, Kuo WW, Huang CY. Pai P, et al. J Cell Biochem. 2018 Sep;119(9):7855-7864. doi: 10.1002/jcb.27199. Epub 2018 Jun 22. J Cell Biochem. 2018. PMID: 29932238
Therefore, in this study, we have analyzed the cardioprotective effects and mechanisms of E2 and/or ERbeta against ZAK overexpression-induced cellular hypertrophy. We have used transient transfection to overexpress ERbeta into the ZAK tet-on H9c2 cells that harbor t …
Therefore, in this study, we have analyzed the cardioprotective effects and mechanisms of E2 and/or ERbeta against ZAK overexpression …
Mixed lineage kinase ZAK promotes epithelial-mesenchymal transition in cancer progression.
Li L, Su N, Zhou T, Zheng D, Wang Z, Chen H, Yuan S, Li W. Li L, et al. Cell Death Dis. 2018 Feb 2;9(2):143. doi: 10.1038/s41419-017-0161-x. Cell Death Dis. 2018. PMID: 29396440 Free PMC article.
ZAK, a mixed lineage kinase, is often described as a positive or negative regulator of cell growth. ...Through combination with ZAK, prognostic accuracy of other common clinicopathological markers in breast cancer is improved by up to 21%. ...
ZAK, a mixed lineage kinase, is often described as a positive or negative regulator of cell growth. ...Through combination with ZA …
ZAK induces cardiomyocyte hypertrophy and brain natriuretic peptide expression via p38/JNK signaling and GATA4/c-Jun transcriptional factor activation.
Hsieh YL, Tsai YL, Shibu MA, Su CC, Chung LC, Pai P, Kuo CH, Yeh YL, Viswanadha VP, Huang CY. Hsieh YL, et al. Mol Cell Biochem. 2015 Jul;405(1-2):1-9. doi: 10.1007/s11010-015-2389-z. Epub 2015 Apr 14. Mol Cell Biochem. 2015. PMID: 25869677
This study evaluates, cellular events associated with the expression of two doxycycline (Dox) inducible Tet-on ZAK expression systems, a Tet-on ZAK WT (wild-type), and a Tet-on ZAK DN (mutant, Dominant-negative form) in H9c2 myoblast cells; Tet-on ZAK …
This study evaluates, cellular events associated with the expression of two doxycycline (Dox) inducible Tet-on ZAK expression systems …
The MAP3K ZAK, a novel modulator of ERK-dependent migration, is upregulated in colorectal cancer.
Rey C, Faustin B, Mahouche I, Ruggieri R, Brulard C, Ichas F, Soubeyran I, Lartigue L, De Giorgi F. Rey C, et al. Oncogene. 2016 Jun 16;35(24):3190-200. doi: 10.1038/onc.2015.379. Epub 2015 Nov 2. Oncogene. 2016. PMID: 26522728
Here, we show that both isoforms of ZAK, ZAK-alpha and ZAK-beta are key factors in cancer cell migration. ...Pharmacological inhibition of ZAK by nilotinib, preventing ZAK-autophosphorylation and thereby auto-activation, led to the same results. …
Here, we show that both isoforms of ZAK, ZAK-alpha and ZAK-beta are key factors in cancer cell migration. ...Pharmacolo …
Leucine-zipper and Sterile-alpha Motif Kinase (ZAK): A Potential Target for Drug Discovery.
Chang Y, Zhang Q, Li Z, Ding K, Lu X. Chang Y, et al. Curr Med Chem. 2016;23(33):3801-3812. doi: 10.2174/0929867323666160920104121. Curr Med Chem. 2016. PMID: 27655071 Review.
Leucine-zipper and sterile-alpha motif kinase (ZAK) is a member of mixed-lineage kinase family (MLKs), which is considered as a new potential target for different physiological disorders, including myocardial hypertrophy and cardiac fibrosis, inflammation and cancer. ...On …
Leucine-zipper and sterile-alpha motif kinase (ZAK) is a member of mixed-lineage kinase family (MLKs), which is considered as a new p …
[Atypical lymphocytes].
Kasprzycka E, Zak J, Ratomski K, Wysocka J. Kasprzycka E, et al. Pol Merkur Lekarski. 2008 May;24(143):443-5. Pol Merkur Lekarski. 2008. PMID: 18634392 Review. Polish.
632 results