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Depleting hepatitis B virus relaxed circular DNA is necessary for resolution of infection by CRISPR-Cas9.
Kostyushev D, Kostyusheva A, Brezgin S, Ponomareva N, Zakirova NF, Egorshina A, Yanvarev DV, Bayurova E, Sudina A, Goptar I, Nikiforova A, Dunaeva E, Lisitsa T, Abramov I, Frolova A, Lukashev A, Gordeychuk I, Zamyatnin AA Jr, Ivanov A, Chulanov V. Kostyushev D, et al. Among authors: nikiforova a. Mol Ther Nucleic Acids. 2023 Feb 4;31:482-493. doi: 10.1016/j.omtn.2023.02.001. eCollection 2023 Mar 14. Mol Ther Nucleic Acids. 2023. PMID: 36865089 Free PMC article.
Transient and tunable CRISPRa regulation of APOBEC/AID genes for targeting hepatitis B virus.
Kostyushev D, Brezgin S, Kostyusheva A, Ponomareva N, Bayurova E, Zakirova N, Kondrashova A, Goptar I, Nikiforova A, Sudina A, Babin Y, Gordeychuk I, Lukashev A, Zamyatnin AA Jr, Ivanov A, Chulanov V. Kostyushev D, et al. Among authors: nikiforova a. Mol Ther Nucleic Acids. 2023 Apr 20;32:478-493. doi: 10.1016/j.omtn.2023.04.016. eCollection 2023 Jun 13. Mol Ther Nucleic Acids. 2023. PMID: 37187708 Free PMC article.