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Page 1
The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation.
Wang S, Link F, Han M, Chaudhary R, Asimakopoulos A, Liebe R, Yao Y, Hammad S, Dropmann A, Krizanac M, Rubie C, Feiner LK, Glanemann M, Ebert MPA, Weiskirchen R, Henis YI, Ehrlich M, Dooley S. Wang S, et al. Among authors: asimakopoulos a. Cell Mol Gastroenterol Hepatol. 2024;17(4):567-587. doi: 10.1016/j.jcmgh.2023.12.012. Epub 2023 Dec 27. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38154598 Free PMC article.
Perilipin 5 deletion protects against nonalcoholic fatty liver disease and hepatocellular carcinoma by modulating lipid metabolism and inflammatory responses.
Mass-Sanchez PB, Krizanac M, Štancl P, Leopold M, Engel KM, Buhl EM, van Helden J, Gassler N, Schiller J, Karlić R, Möckel D, Lammers T, Meurer SK, Weiskirchen R, Asimakopoulos A. Mass-Sanchez PB, et al. Among authors: asimakopoulos a. Cell Death Discov. 2024 Feb 22;10(1):94. doi: 10.1038/s41420-024-01860-4. Cell Death Discov. 2024. PMID: 38388533 Free PMC article.
IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis.
Eslam M, McLeod D, Kelaeng KS, Mangia A, Berg T, Thabet K, Irving WL, Dore GJ, Sheridan D, Grønbæk H, Abate ML, Hartmann R, Bugianesi E, Spengler U, Rojas A, Booth DR, Weltman M, Mollison L, Cheng W, Riordan S, Mahajan H, Fischer J, Nattermann J, Douglas MW, Liddle C, Powell E, Romero-Gomez M, George J; International Liver Disease Genetics Consortium (ILDGC). Eslam M, et al. Nat Genet. 2017 May;49(5):795-800. doi: 10.1038/ng.3836. Epub 2017 Apr 10. Nat Genet. 2017. PMID: 28394349 Free article.
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C.
Thabet K, Asimakopoulos A, Shojaei M, Romero-Gomez M, Mangia A, Irving WL, Berg T, Dore GJ, Grønbæk H, Sheridan D, Abate ML, Bugianesi E, Weltman M, Mollison L, Cheng W, Riordan S, Fischer J, Spengler U, Nattermann J, Wahid A, Rojas A, White R, Douglas MW, McLeod D, Powell E, Liddle C, van der Poorten D, George J, Eslam M; International Liver Disease Genetics Consortium. Thabet K, et al. Among authors: asimakopoulos a. Nat Commun. 2016 Sep 15;7:12757. doi: 10.1038/ncomms12757. Nat Commun. 2016. PMID: 27630043 Free PMC article.