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LAIR-1 agonism as a therapy for acute myeloid leukemia.
Lovewell RR, Hong J, Kundu S, Fielder CM, Hu Q, Kim KW, Ramsey HE, Gorska AE, Fuller LS, Tian L, Kothari P, Paucarmayta A, Mason EF, Meza I, Manzanarez Y, Bosiacki J, Maloveste K, Mitchell N, Barbu EA, Morawski A, Maloveste S, Cusumano Z, Patel SJ, Savona MR, Langermann S, Myint H, Flies DB, Kim TK. Lovewell RR, et al. Among authors: paucarmayta a. J Clin Invest. 2023 Nov 15;133(22):e169519. doi: 10.1172/JCI169519. J Clin Invest. 2023. PMID: 37966113 Free PMC article.
Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction.
Ramos MIP, Tian L, de Ruiter EJ, Song C, Paucarmayta A, Singh A, Elshof E, Vijver SV, Shaik J, Bosiacki J, Cusumano Z, Jensen C, Willumsen N, Karsdal MA, Liu L, Langermann S, Willems S, Flies D, Meyaard L. Ramos MIP, et al. Among authors: paucarmayta a. Elife. 2021 Jun 14;10:e62927. doi: 10.7554/eLife.62927. Elife. 2021. PMID: 34121658 Free PMC article.
The FLRT3-UNC5B checkpoint pathway inhibits T cell-based cancer immunotherapies.
Prajapati K, Yan C, Yang Q, Arbitman S, Fitzgerald DP, Sharee S, Shaik J, Bosiacki J, Myers K, Paucarmayta A, Johnson DM, O'Neill T, Kundu S, Cusumano Z, Langermann S, Langenau DM, Patel S, Flies DB. Prajapati K, et al. Among authors: paucarmayta a. Sci Adv. 2024 Mar;10(9):eadj4698. doi: 10.1126/sciadv.adj4698. Epub 2024 Mar 1. Sci Adv. 2024. PMID: 38427724 Free PMC article.