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Year Number of Results
1946 1
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1949 1
1950 2
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1954 3
1955 1
1957 1
1958 2
1960 3
1961 1
1962 7
1963 5
1964 7
1965 13
1966 10
1967 17
1968 15
1969 22
1970 19
1971 40
1972 38
1973 38
1974 55
1975 166
1976 167
1977 148
1978 146
1979 216
1980 281
1981 326
1982 452
1983 690
1984 836
1985 961
1986 1128
1987 1178
1988 1182
1989 1196
1990 1195
1991 1230
1992 1267
1993 1264
1994 1230
1995 1254
1996 1163
1997 1032
1998 999
1999 1032
2000 1175
2001 1024
2002 1070
2003 989
2004 1080
2005 954
2006 881
2007 945
2008 951
2009 926
2010 1001
2011 972
2012 955
2013 954
2014 909
2015 955
2016 899
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2018 834
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2024 281

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Page 1
Showing results for and leu
Search for Ana Lea instead (3 results)
Exploring Conformational Preferences of Leu-enkephalin Using the Conformational Search and Double-Hybrid DFT Energy Calculations.
Park HS, Byun BJ, Kang YK. Park HS, et al. ACS Omega. 2022 Jul 26;7(31):27755-27768. doi: 10.1021/acsomega.2c03942. eCollection 2022 Aug 9. ACS Omega. 2022. PMID: 35967045 Free PMC article.
The conformational preferences of Leu-enkephalin (Leu-Enk) were explored by the conformational search and density functional theory (DFT) calculations. ...According to the refined model of the zwitterionic Leu-Enk bound to delta-opioid receptor (deltaOR), the …
The conformational preferences of Leu-enkephalin (Leu-Enk) were explored by the conformational search and density functional t …
Velcrin-induced selective cleavage of tRNA(Leu)(TAA) by SLFN12 causes cancer cell death.
Lee S, Hoyt S, Wu X, Garvie C, McGaunn J, Shekhar M, Tötzl M, Rees MG, Cherniack AD, Meyerson M, Greulich H. Lee S, et al. Nat Chem Biol. 2023 Mar;19(3):301-310. doi: 10.1038/s41589-022-01170-9. Epub 2022 Oct 27. Nat Chem Biol. 2023. PMID: 36302897
Here, we report that the physiological substrate of SLFN12 RNase is tRNA(Leu)(TAA). SLFN12 selectively digests tRNA(Leu)(TAA), and velcrin treatment promotes the cleavage of tRNA(Leu)(TAA) by inducing PDE3A-SLFN12 complex formation in vitro. We found that dis …
Here, we report that the physiological substrate of SLFN12 RNase is tRNA(Leu)(TAA). SLFN12 selectively digests tRNA(Leu)(TAA), …
Sculpting Secondary Structure of a Cyclic Peptide: Conformational Analysis of a Cyclic Hexapeptide Containing a Combination of l-Leu, d-Leu, and Aib Residues.
Ito T, Yokoo H, Kato T, Doi M, Demizu Y. Ito T, et al. ACS Omega. 2023 Nov 8;8(46):44106-44111. doi: 10.1021/acsomega.3c06397. eCollection 2023 Nov 21. ACS Omega. 2023. PMID: 38027316 Free PMC article.
We have previously reported that cyclo(l-Leu-d-Leu-Aib-l-Leu-d-Leu-Aib) (2), a cyclic hexapeptide consisting of heterochiral l-Leu and d-Leu (l-Leu-d-Leu) residues with achiral 2-aminoisobutyric acid (Aib) residues, forms a …
We have previously reported that cyclo(l-Leu-d-Leu-Aib-l-Leu-d-Leu-Aib) (2), a cyclic hexapeptide consisting of …
Effects of L-Leu-L-Leu peptide on growth, proliferation, and apoptosis in broiler intestinal epithelial cells.
Liang J, Du B, Wan M, Sun L, Qin S, Nian F, Tang D. Liang J, et al. Poult Sci. 2024 Feb 22;103(5):103582. doi: 10.1016/j.psj.2024.103582. Online ahead of print. Poult Sci. 2024. PMID: 38457989 Free article.
We here cultured the primary small intestinal epithelial cells (IEC) of chicken in a medium containing L-Leu (Leu) and L-Leu-L-Leu (Leu-Leu) for 24 h. The untreated cells were considered as the control group. ...In short, Leu-Le …
We here cultured the primary small intestinal epithelial cells (IEC) of chicken in a medium containing L-Leu (Leu) and L-Le …
Multiple roles of Leu-8/MEL-14 in leukocyte adhesion and function.
James SP, Murakawa Y, Kanof ME, Berg M. James SP, et al. Immunol Res. 1991;10(3-4):282-92. doi: 10.1007/BF02919708. Immunol Res. 1991. PMID: 1720159 Review.
In addition to its role in leukocyte adhesion, there is evidence that the Leu-8 molecule plays a role in cell function. Anti-Leu-8 monoclonal antibody increases suppressor activity of CD4+, Leu-8+ T cells for immunoglobulin synthesis, and anti-Leu-8 di …
In addition to its role in leukocyte adhesion, there is evidence that the Leu-8 molecule plays a role in cell function. Anti-Leu …
Peptide (Lys-Leu) and amino acids (Lys and Leu) supplementations improve physiological activity and fermentation performance of brewer's yeast during very high-gravity (VHG) wort fermentation.
Yang H, Zong X, Cui C, Mu L, Zhao H. Yang H, et al. Biotechnol Appl Biochem. 2018 Jul;65(4):630-638. doi: 10.1002/bab.1634. Epub 2018 Jan 16. Biotechnol Appl Biochem. 2018. PMID: 29271090
In the present study, peptide Lys-Leu and a free amino acid (FAA) mixture of Lys and Leu (Lys + Leu) were supplemented in 24 P wort to examine their effects on physiological activity and fermentation performance of brewer's yeast during very high-gravity (VHG …
In the present study, peptide Lys-Leu and a free amino acid (FAA) mixture of Lys and Leu (Lys + Leu) were supplemented …
Identification of isomeric cyclo(leu-pro) produced by Pseudomonas sesami BC42 and its differential antifungal activities against Colletotrichum orbiculare.
Kim J, Kim JC, Sang MK. Kim J, et al. Front Microbiol. 2023 Aug 10;14:1230345. doi: 10.3389/fmicb.2023.1230345. eCollection 2023. Front Microbiol. 2023. PMID: 37637119 Free PMC article.
In this work, preparative thin-layer chromatography was conducted to identify the antifungal compounds in the extract of strain BC42, and the portion of the extract that exhibited antifungal activity was further analyzed by gas chromatography-mass spectrometry. Three different is …
In this work, preparative thin-layer chromatography was conducted to identify the antifungal compounds in the extract of strain BC42, and th …
Glutamine and leucine administration attenuates muscle atrophy in sepsis.
Hou YC, Wu JM, Chen KY, Wu MH, Yang PJ, Lee PC, Chen PD, Yeh SL, Lin MT. Hou YC, et al. Life Sci. 2023 Feb 1;314:121327. doi: 10.1016/j.lfs.2022.121327. Epub 2022 Dec 27. Life Sci. 2023. PMID: 36584912
MATERIALS AND METHODS: Septic mice were given a daily intraperitoneal injection of Gln, Leu, or Gln plus Leu, and mice were sacrificed on either day 1 or 4 after CLP. ...As to muscle expressions of myogenic genes, both Gln and Leu upregulated Myog expression …
MATERIALS AND METHODS: Septic mice were given a daily intraperitoneal injection of Gln, Leu, or Gln plus Leu, and mice were sa …
Co-ingestion of glutamine and leucine synergistically promotes mTORC1 activation.
Yoshimura R, Nomura S. Yoshimura R, et al. Sci Rep. 2022 Sep 23;12(1):15870. doi: 10.1038/s41598-022-20251-2. Sci Rep. 2022. PMID: 36151270 Free PMC article.
To resolve this paradox, we aimed to elucidate the effects of Gln on Leu-mediated mTORC1 activation. We administered Leu, Gln, tryptophan, Leu + Gln, or Leu + tryptophan to mice after 24-h fasting. ...No difference in glutamate dehydrogenase activity w …
To resolve this paradox, we aimed to elucidate the effects of Gln on Leu-mediated mTORC1 activation. We administered Leu, Gln, …
Met- and leu-enkephalin immuno- and bio-reactivity in human stomach and pancreas.
Feurle GE, Helmstaedter V, Weber U. Feurle GE, et al. Life Sci. 1982 Dec 27;31(26):2961-9. doi: 10.1016/0024-3205(82)90062-5. Life Sci. 1982. PMID: 7162359
As the assays for leu-enkephalin crossreacted with those for met-enkephalin, only cyanogen bromide-treated samples were used for the determination of leu enkephalin. ...Met- and leu-enkephalin receptor bioreactivity concentrations exceeded immunoreactivity co …
As the assays for leu-enkephalin crossreacted with those for met-enkephalin, only cyanogen bromide-treated samples were used for the …
41,330 results
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