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The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction.
Walsh SC, Reitano JR, Dickinson MS, Kutsch M, Hernandez D, Barnes AB, Schott BH, Wang L, Ko DC, Kim SY, Valdivia RH, Bastidas RJ, Coers J. Walsh SC, et al. Among authors: barnes ab. Cell Host Microbe. 2022 Dec 14;30(12):1671-1684.e9. doi: 10.1016/j.chom.2022.08.008. Epub 2022 Sep 8. Cell Host Microbe. 2022. PMID: 36084633 Free PMC article.
The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection.
Nelson EA, Dyall J, Hoenen T, Barnes AB, Zhou H, Liang JY, Michelotti J, Dewey WH, DeWald LE, Bennett RS, Morris PJ, Guha R, Klumpp-Thomas C, McKnight C, Chen YC, Xu X, Wang A, Hughes E, Martin S, Thomas C, Jahrling PB, Hensley LE, Olinger GG Jr, White JM. Nelson EA, et al. Among authors: barnes ab. PLoS Negl Trop Dis. 2017 Apr 12;11(4):e0005540. doi: 10.1371/journal.pntd.0005540. eCollection 2017 Apr. PLoS Negl Trop Dis. 2017. PMID: 28403145 Free PMC article.