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Showing results for saline d. jacob
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Intramuscular AZD7442 (Tixagevimab-Cilgavimab) for Prevention of Covid-19.
Levin MJ, Ustianowski A, De Wit S, Launay O, Avila M, Templeton A, Yuan Y, Seegobin S, Ellery A, Levinson DJ, Ambery P, Arends RH, Beavon R, Dey K, Garbes P, Kelly EJ, Koh GCKW, Near KA, Padilla KW, Psachoulia K, Sharbaugh A, Streicher K, Pangalos MN, Esser MT; PROVENT Study Group. Levin MJ, et al. N Engl J Med. 2022 Jun 9;386(23):2188-2200. doi: 10.1056/NEJMoa2116620. Epub 2022 Apr 20. N Engl J Med. 2022. PMID: 35443106 Free PMC article. Clinical Trial.
Participants were randomly assigned in a 2:1 ratio to receive a single dose (two consecutive intramuscular injections, one containing tixagevimab and the other containing cilgavimab) of either 300 mg of AZD7442 or saline placebo, and they were followed for up to 183 days i …
Participants were randomly assigned in a 2:1 ratio to receive a single dose (two consecutive intramuscular injections, one containing tixage …
Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial.
Alton EWFW, Armstrong DK, Ashby D, Bayfield KJ, Bilton D, Bloomfield EV, Boyd AC, Brand J, Buchan R, Calcedo R, Carvelli P, Chan M, Cheng SH, Collie DDS, Cunningham S, Davidson HE, Davies G, Davies JC, Davies LA, Dewar MH, Doherty A, Donovan J, Dwyer NS, Elgmati HI, Featherstone RF, Gavino J, Gea-Sorli S, Geddes DM, Gibson JSR, Gill DR, Greening AP, Griesenbach U, Hansell DM, Harman K, Higgins TE, Hodges SL, Hyde SC, Hyndman L, Innes JA, Jacob J, Jones N, Keogh BF, Limberis MP, Lloyd-Evans P, Maclean AW, Manvell MC, McCormick D, McGovern M, McLachlan G, Meng C, Montero MA, Milligan H, Moyce LJ, Murray GD, Nicholson AG, Osadolor T, Parra-Leiton J, Porteous DJ, Pringle IA, Punch EK, Pytel KM, Quittner AL, Rivellini G, Saunders CJ, Scheule RK, Sheard S, Simmonds NJ, Smith K, Smith SN, Soussi N, Soussi S, Spearing EJ, Stevenson BJ, Sumner-Jones SG, Turkkila M, Ureta RP, Waller MD, Wasowicz MY, Wilson JM, Wolstenholme-Hogg P; UK Cystic Fibrosis Gene Therapy Consortium. Alton EWFW, et al. Lancet Respir Med. 2015 Sep;3(9):684-691. doi: 10.1016/S2213-2600(15)00245-3. Epub 2015 Jul 3. Lancet Respir Med. 2015. PMID: 26149841 Free PMC article. Clinical Trial.
Patients (aged 12 years) with a forced expiratory volume in 1 s (FEV1) of 50-90% predicted and any combination of CFTR mutations, were randomly assigned, via a computer-based randomisation system, to receive 5 mL of either nebulised pGM169/GL67A gene-liposome complex or 0.9% s …
Patients (aged 12 years) with a forced expiratory volume in 1 s (FEV1) of 50-90% predicted and any combination of CFTR mutations, were rando …
Strain-dependent lung transcriptomic differences in cigarette smoke and LPS models of lung injury in mice.
Siamwala JH, Mossman JA, Schorl C, Borgas D, Sakhatskyy P, Rand DM, Lu Q, Rounds S. Siamwala JH, et al. Physiol Genomics. 2023 Jun 1;55(6):259-274. doi: 10.1152/physiolgenomics.00152.2022. Epub 2023 May 15. Physiol Genomics. 2023. PMID: 37184227
Am J Respir Crit Care Med 183: 1660-1665, 2011; Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, Havel C, Benowitz NL, Ware LB. Crit Care Med 43: 1790-1797, 2015; Toy P, Gajic O, Bacchetti P, Looney MR, Gropper MA, Hubmayr R, Lowell CA, …
Am J Respir Crit Care Med 183: 1660-1665, 2011; Calfee CS, Matthay MA, Kangelaris KN, Siew ED, Janz DR, Bernard GR, May AK, Jacob P, …
Effect of Hydroxyethyl Starch vs Saline for Volume Replacement Therapy on Death or Postoperative Complications Among High-Risk Patients Undergoing Major Abdominal Surgery: The FLASH Randomized Clinical Trial.
Futier E, Garot M, Godet T, Biais M, Verzilli D, Ouattara A, Huet O, Lescot T, Lebuffe G, Dewitte A, Cadic A, Restoux A, Asehnoune K, Paugam-Burtz C, Cuvillon P, Faucher M, Vaisse C, El Amine Y, Beloeil H, Leone M, Noll E, Piriou V, Lasocki S, Bazin JE, Pereira B, Jaber S; FLASH Trial Group; Lasocki S, Huet O, Cadic A, Jacob C, Paugam-Burtz C, Restoux A, Ouattara A, Feitita I, Deloge E, Defaye M, Joannes-Boyau O, Carles P, Napolitano G, Monziols S, Futier E, Vignaud M, Paul S, Gahbiche K, Fayon J, Laroche E, Bazin JE, Brandely A, Le Moal C, Lebuffe G, Garot M, Piriou V, Jaber S, Chanques G, Verzilli D, De Jong A, Millot A, Castagnoli A, Leone M, Pastene B, Castelli C, Medam S, Velly L, Vaisse C, Faucher M, Asehnoune K, Samba E, Roquilly A, Le Penndu M, Cuvillon P, Yves Lefrant J, Wira O, Dubout E, Mfam WS, Lescot T, Begneu E, Burey J, Cirilovic T, Beloeil H, Allo G, Pottecher J, Lebas B, Venot C, Rameau JP, Dimache F, Léger PS, El Amine Y. Futier E, et al. JAMA. 2020 Jan 21;323(3):225-236. doi: 10.1001/jama.2019.20833. JAMA. 2020. PMID: 31961418 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate the effect of HES 130/0.4 compared with 0.9% saline for intravascular volume expansion on mortality and postoperative complications after major abdominal surgery. ...INTERVENTIONS: Patients were randomized to receive fluid containing either 6% HES 13 …
OBJECTIVE: To evaluate the effect of HES 130/0.4 compared with 0.9% saline for intravascular volume expansion on mortality and postop …
Radionuclide transport in brackish water through chalk fractures.
Tran EL, Teutsch N, Klein-BenDavid O, Kersting AB, Zavrin M, Weisbrod N. Tran EL, et al. Water Res. 2019 Oct 15;163:114886. doi: 10.1016/j.watres.2019.114886. Epub 2019 Jul 18. Water Res. 2019. PMID: 31357014
Rhenium transport was identical to that of the conservative tracer, uranine. The sorption coefficient (K(d)) of U(VI), Cs and Re, calculated from batch experiments with crushed chalk, proved to be a good predictor of mass recovery in transport experiments conducted without …
Rhenium transport was identical to that of the conservative tracer, uranine. The sorption coefficient (K(d)) of U(VI), Cs and Re, cal …
Leveraging a graft collection to develop metabolome-based trait prediction for the selection of tomato rootstocks with enhanced salt tolerance.
Song C, Acuña T, Adler-Agmon M, Rachmilevitch S, Barak S, Fait A. Song C, et al. Hortic Res. 2022 Mar 14;9:uhac061. doi: 10.1093/hr/uhac061. eCollection 2022. Hortic Res. 2022. PMID: 35531316 Free PMC article.
We grafted the scion of cultivated M82 onto rootstocks of 254 tomato accessions and explored the morphological and metabolic responses of grafts under saline conditions (EC = 20 dS m(-1)) as compared to self-grafted M82 (SG-M82). ...
We grafted the scion of cultivated M82 onto rootstocks of 254 tomato accessions and explored the morphological and metabolic responses of gr …
Inhibition of lipogenesis reduces inflammation and organ injury in sepsis.
Idrovo JP, Yang WL, Jacob A, Corbo L, Nicastro J, Coppa GF, Wang P. Idrovo JP, et al. J Surg Res. 2016 Jan;200(1):242-9. doi: 10.1016/j.jss.2015.06.059. Epub 2015 Jul 2. J Surg Res. 2016. PMID: 26216747 Free PMC article.
At 4 h after CLP, different doses of C75 (1- or 5-mg/kg body weight) or vehicle (20% dimethyl sulfoxide in saline) were injected intraperitoneally. Blood and liver tissues were collected at 24 h after CLP. ...In the liver, C75 treatment reduced inflammation (TNF-alpha and …
At 4 h after CLP, different doses of C75 (1- or 5-mg/kg body weight) or vehicle (20% dimethyl sulfoxide in saline) were injected intr …
[Value of hormonal treatment with triiodothyronine and cortisone in brain dead patients].
Mariot J, Jacob F, Voltz C, Perrier JF, Strub P. Mariot J, et al. Ann Fr Anesth Reanim. 1991;10(4):321-8. doi: 10.1016/s0750-7658(05)80806-8. Ann Fr Anesth Reanim. 1991. PMID: 1928853 Review. French.
Forty adult brain-dead patients were randomly assigned to two groups, the patients of the treated group were given every hour, or half hour, 2 or 4 micrograms T3 and 100 mg hydrocortisone intravenously, and those of the placebo group normal saline. Both groups of patients …
Forty adult brain-dead patients were randomly assigned to two groups, the patients of the treated group were given every hour, or half hour, …
Inhalation of a Short-Acting β2-Adrenoreceptor Agonist Induces a Hypercoagulable State in Healthy Subjects.
Ali-Saleh M, Sarig G, Ablin JN, Brenner B, Jacob G. Ali-Saleh M, et al. PLoS One. 2016 Jul 5;11(7):e0158652. doi: 10.1371/journal.pone.0158652. eCollection 2016. PLoS One. 2016. PMID: 27379911 Free PMC article. Clinical Trial.
METHODS: We recruited 23 healthy volunteers (nine females; mean age: 260.8 years; body mass index: 24.70.5 kg/m2) and randomly allocated them into two groups, the beta2AR arm (seventeen subjects) and the saline arm (six subjects). Hemodynamics, plasma norepinephrine concen …
METHODS: We recruited 23 healthy volunteers (nine females; mean age: 260.8 years; body mass index: 24.70.5 kg/m2) and randomly allocated the …
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