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Page 1
New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models.
Eur J Med Chem. 2022 Aug 5;238:114435. doi: 10.1016/j.ejmech.2022.114435. Epub 2022 May 12.
Eur J Med Chem. 2022.
PMID: 35598411
β-Lactam TRPM8 Antagonist RGM8-51 Displays Antinociceptive Activity in Different Animal Models.
Martín-Escura C, Medina-Peris A, Spear LA, de la Torre Martínez R, Olivos-Oré LA, Barahona MV, González-Rodríguez S, Fernández-Ballester G, Fernández-Carvajal A, Artalejo AR, Ferrer-Montiel A, González-Muñiz R.
Martín-Escura C, et al. Among authors: medina peris a.
Int J Mol Sci. 2022 Feb 28;23(5):2692. doi: 10.3390/ijms23052692.
Int J Mol Sci. 2022.
PMID: 35269831
Free PMC article.
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β-Lactam TRPM8 Antagonists Derived from Phe-Phenylalaninol Conjugates: Structure-Activity Relationships and Antiallodynic Activity.
Martín-Escura C, Bonache MÁ, Medina JA, Medina-Peris A, De Andrés-López J, González-Rodríguez S, Kerselaers S, Fernández-Ballester G, Voets T, Ferrer-Montiel A, Fernández-Carvajal A, González-Muñiz R.
Martín-Escura C, et al. Among authors: medina peris a.
Int J Mol Sci. 2023 Oct 4;24(19):14894. doi: 10.3390/ijms241914894.
Int J Mol Sci. 2023.
PMID: 37834342
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Phenylalanine-Derived β-Lactam TRPM8 Modulators. Configuration Effect on the Antagonist Activity.
Bonache MÁ, Llabrés PJ, Martín-Escura C, De la Torre-Martínez R, Medina-Peris A, Butrón L, Gómez-Monterrey I, Roa AM, Fernández-Ballester G, Ferrer-Montiel A, Fernández-Carvajal A, González-Muñiz R.
Bonache MÁ, et al. Among authors: medina peris a.
Int J Mol Sci. 2021 Feb 27;22(5):2370. doi: 10.3390/ijms22052370.
Int J Mol Sci. 2021.
PMID: 33673444
Free PMC article.
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In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening.
Iraci N, Ostacolo C, Medina-Peris A, Ciaglia T, Novoselov AM, Altieri A, Cabañero D, Fernandez-Carvajal A, Campiglia P, Gomez-Monterrey I, Bertamino A, Kurkin AV.
Iraci N, et al. Among authors: medina peris a.
Int J Mol Sci. 2022 Feb 13;23(4):2070. doi: 10.3390/ijms23042070.
Int J Mol Sci. 2022.
PMID: 35216186
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