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Page 1
Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.
J Med Chem. 2021 Aug 12;64(15):10849-10877. doi: 10.1021/acs.jmedchem.0c02274. Epub 2021 Jul 15.
J Med Chem. 2021.
PMID: 34264658
Free PMC article.
SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4.
Tiek D, Wells CI, Schröder M, Song X, Alamillo-Ferrer C, Goenka A, Iglesia R, Lu M, Hu B, Kwarcinski F, Sintha P, de Silva C, Hossain MA, Picado A, Zuercher W, Zutshi R, Knapp S, Riggins RB, Cheng SY, Drewry DH.
Tiek D, et al. Among authors: picado a.
Curr Res Chem Biol. 2023;3:100045. doi: 10.1016/j.crchbi.2023.100045. Epub 2023 Sep 22.
Curr Res Chem Biol. 2023.
PMID: 38009092
Free PMC article.
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Towards a RIOK2 chemical probe: cellular potency improvement of a selective 2-(acylamino)pyridine series.
Wang CB, Lorente-Macías Á, Wells C, Pickett JE, Picado A, Zuercher WJ, Axtman AD.
Wang CB, et al. Among authors: picado a.
RSC Med Chem. 2020 Nov 11;12(1):129-136. doi: 10.1039/d0md00292e. eCollection 2021 Jan 1.
RSC Med Chem. 2020.
PMID: 34046605
Free PMC article.
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The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification.
Wells CI, Al-Ali H, Andrews DM, Asquith CRM, Axtman AD, Dikic I, Ebner D, Ettmayer P, Fischer C, Frederiksen M, Futrell RE, Gray NS, Hatch SB, Knapp S, Lücking U, Michaelides M, Mills CE, Müller S, Owen D, Picado A, Saikatendu KS, Schröder M, Stolz A, Tellechea M, Turunen BJ, Vilar S, Wang J, Zuercher WJ, Willson TM, Drewry DH.
Wells CI, et al. Among authors: picado a.
Int J Mol Sci. 2021 Jan 8;22(2):566. doi: 10.3390/ijms22020566.
Int J Mol Sci. 2021.
PMID: 33429995
Free PMC article.
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A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation.
Picado A, Chaikuad A, Wells CI, Shrestha S, Zuercher WJ, Pickett JE, Kwarcinski FE, Sinha P, de Silva CS, Zutshi R, Liu S, Kannan N, Knapp S, Drewry DH, Willson TM.
Picado A, et al.
J Med Chem. 2020 Dec 10;63(23):14626-14646. doi: 10.1021/acs.jmedchem.0c01174. Epub 2020 Nov 20.
J Med Chem. 2020.
PMID: 33215924
Free PMC article.
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A Serendipitous Synthesis of Bis-Heterocyclic Spiro 3(2H)-Furanones.
Picado A, Li S, Dieter RK.
Picado A, et al.
J Org Chem. 2016 Feb 19;81(4):1391-400. doi: 10.1021/acs.joc.5b02350. Epub 2016 Feb 10.
J Org Chem. 2016.
PMID: 26756271
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Regio- and stereocontrol in the reactions of α-halo-β,γ-enoates and α-O-phosphono-β,γ-enenitriles with organocuprates.
Dieter RK, Picado A.
Dieter RK, et al. Among authors: picado a.
J Org Chem. 2014 Nov 21;79(22):11125-38. doi: 10.1021/jo502111c. Epub 2014 Nov 3.
J Org Chem. 2014.
PMID: 25303237
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