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Page 1
Showing results for alexander inclusion
Search for Alexander Incledion instead (1 results)
Management of thyroid nodules.
Alexander EK, Doherty GM, Barletta JA. Alexander EK, et al. Lancet Diabetes Endocrinol. 2022 Jul;10(7):540-548. doi: 10.1016/S2213-8587(22)00139-5. Lancet Diabetes Endocrinol. 2022. PMID: 35752201 Review.
In summary, modern management strategies for thyroid nodular disease seek to incorporate the growing amount of available diagnostic and prognostic data, inclusive of demographic, radiological, pathological and molecular findings. ...
In summary, modern management strategies for thyroid nodular disease seek to incorporate the growing amount of available diagnostic and prog …
Myelin changes in Alexander disease.
Gómez-Pinedo U, Duran-Moreno M, Sirerol-Piquer S, Matias-Guiu J. Gómez-Pinedo U, et al. Neurologia (Engl Ed). 2018 Oct;33(8):526-533. doi: 10.1016/j.nrl.2017.01.019. Epub 2017 Mar 22. Neurologia (Engl Ed). 2018. PMID: 28342553 Free article. Review. English, Spanish.
INTRODUCTION: Alexander disease (AxD) is a type of leukodystrophy. Its pathological basis, along with myelin loss, is the appearance of Rosenthal bodies, which are cytoplasmic inclusions in astrocytes. ...
INTRODUCTION: Alexander disease (AxD) is a type of leukodystrophy. Its pathological basis, along with myelin loss, is the appearance …
Peritoneal mesothelioma.
Greenbaum A, Alexander HR. Greenbaum A, et al. Transl Lung Cancer Res. 2020 Feb;9(Suppl 1):S120-S132. doi: 10.21037/tlcr.2019.12.15. Transl Lung Cancer Res. 2020. PMID: 32206577 Free PMC article. Review.
Patients with MPM should be treated at high volume centers with strong consideration for inclusion in tumor registries and clinical trials. In 2020, research will continue to explore promising genetic and immunologic targets and focus on refinement of surgical methods to o …
Patients with MPM should be treated at high volume centers with strong consideration for inclusion in tumor registries and clinical t …
Polymyositis.
Sarwar A, Dydyk AM, Jatwani S. Sarwar A, et al. 2023 Feb 7. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Feb 7. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 33085276 Free Books & Documents.
Idiopathic inflammatory myopathies involve four major subtypes that include polymyositis, dermatomyositis, inclusion body myositis, and necrotizing myopathy. Bohan and Peter categorized myopathies into 7 classes. Polymyositis, an autoimmune and chronic inflammatory myopath …
Idiopathic inflammatory myopathies involve four major subtypes that include polymyositis, dermatomyositis, inclusion body myositis, a …
An alternative splicing modulator decreases mutant HTT and improves the molecular fingerprint in Huntington's disease patient neurons.
Krach F, Stemick J, Boerstler T, Weiss A, Lingos I, Reischl S, Meixner H, Ploetz S, Farrell M, Hehr U, Kohl Z, Winner B, Winkler J. Krach F, et al. Nat Commun. 2022 Nov 10;13(1):6797. doi: 10.1038/s41467-022-34419-x. Nat Commun. 2022. PMID: 36357392 Free PMC article. Clinical Trial.
The drug lowers total HTT (tHTT) and mHTT levels in fibroblasts, iPSC, cortical progenitors, and neurons in a dose dependent manner at an IC(50) consistently below 10 nM without inducing cellular toxicity. Branaplam promotes inclusion of non-annotated novel exons. Among th …
The drug lowers total HTT (tHTT) and mHTT levels in fibroblasts, iPSC, cortical progenitors, and neurons in a dose dependent manner at an IC …
Strategies for treatment in Alexander disease.
Messing A, LaPash Daniels CM, Hagemann TL. Messing A, et al. Neurotherapeutics. 2010 Oct;7(4):507-15. doi: 10.1016/j.nurt.2010.05.013. Neurotherapeutics. 2010. PMID: 20880512 Free PMC article. Review.
Alexander disease is a rare and generally fatal disorder of the CNS, originally classified among the leukodystrophies because of the prominent myelin deficits found in young patients. The most common form of this disease affects infants, who often have profound mental reta …
Alexander disease is a rare and generally fatal disorder of the CNS, originally classified among the leukodystrophies because of the …
[Toxic megacolon].
Leppkes M, Ganslmayer M, Strauß R, Neurath MF. Leppkes M, et al. Med Klin Intensivmed Notfmed. 2015 Oct;110(7):500-5. doi: 10.1007/s00063-015-0076-1. Epub 2015 Sep 14. Med Klin Intensivmed Notfmed. 2015. PMID: 26369529 Review. German.
Juvenile Alexander Disease: A Rare Leukodystrophy.
Ullah R, Wazir MH, Gul A, Gul F, Arshad A. Ullah R, et al. Cureus. 2022 May 10;14(5):e24870. doi: 10.7759/cureus.24870. eCollection 2022 May. Cureus. 2022. PMID: 35698668 Free PMC article.
Alexander disease is an uncommon autosomal dominant leukodystrophy that influences the white matter of the central nervous system (CNS), predominantly affecting the frontal lobe bilaterally. The most obvious pathogenic hallmark is the extensive deposition of cytoplasmic …
Alexander disease is an uncommon autosomal dominant leukodystrophy that influences the white matter of the central nervous system (CN …
1,613 results