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PeakDecoder enables machine learning-based metabolite annotation and accurate profiling in multidimensional mass spectrometry measurements.
Bilbao A, Munoz N, Kim J, Orton DJ, Gao Y, Poorey K, Pomraning KR, Weitz K, Burnet M, Nicora CD, Wilton R, Deng S, Dai Z, Oksen E, Gee A, Fasani RA, Tsalenko A, Tanjore D, Gardner J, Smith RD, Michener JK, Gladden JM, Baker ES, Petzold CJ, Kim YM, Apffel A, Magnuson JK, Burnum-Johnson KE. Bilbao A, et al. Among authors: apffel a. Nat Commun. 2023 Apr 28;14(1):2461. doi: 10.1038/s41467-023-37031-9. Nat Commun. 2023. PMID: 37117207 Free PMC article.
RNA-protein analysis using a conditional CRISPR nuclease.
Lee HY, Haurwitz RE, Apffel A, Zhou K, Smart B, Wenger CD, Laderman S, Bruhn L, Doudna JA. Lee HY, et al. Among authors: apffel a. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5416-21. doi: 10.1073/pnas.1302807110. Epub 2013 Mar 14. Proc Natl Acad Sci U S A. 2013. PMID: 23493562 Free PMC article.
SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids.
Zhang X, Romm M, Zheng X, Zink EM, Kim YM, Burnum-Johnson KE, Orton DJ, Apffel A, Ibrahim YM, Monroe ME, Moore RJ, Smith JN, Ma J, Renslow RS, Thomas DG, Blackwell AE, Swinford G, Sausen J, Kurulugama RT, Eno N, Darland E, Stafford G, Fjeldsted J, Metz TO, Teeguarden JG, Smith RD, Baker ES. Zhang X, et al. Among authors: apffel a. Clin Mass Spectrom. 2016 Dec;2:1-10. doi: 10.1016/j.clinms.2016.11.002. Epub 2016 Dec 29. Clin Mass Spectrom. 2016. PMID: 29276770 Free PMC article.