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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2004 1
2005 2
2006 2
2007 4
2008 1
2009 5
2010 4
2011 3
2012 4
2013 9
2014 7
2015 8
2016 5
2017 6
2018 8
2019 10
2020 8
2021 8
2022 5
2023 5
2024 4

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103 results

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Page 1
Ubiquitin ligases: guardians of mammalian development.
Cruz Walma DA, Chen Z, Bullock AN, Yamada KM. Cruz Walma DA, et al. Among authors: bullock an. Nat Rev Mol Cell Biol. 2022 May;23(5):350-367. doi: 10.1038/s41580-021-00448-5. Epub 2022 Jan 25. Nat Rev Mol Cell Biol. 2022. PMID: 35079164 Review.
Targeted protein degradation: expanding the toolbox.
Schapira M, Calabrese MF, Bullock AN, Crews CM. Schapira M, et al. Among authors: bullock an. Nat Rev Drug Discov. 2019 Dec;18(12):949-963. doi: 10.1038/s41573-019-0047-y. Epub 2019 Oct 30. Nat Rev Drug Discov. 2019. PMID: 31666732
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.
Zhang T, Kwiatkowski N, Olson CM, Dixon-Clarke SE, Abraham BJ, Greifenberg AK, Ficarro SB, Elkins JM, Liang Y, Hannett NM, Manz T, Hao M, Bartkowiak B, Greenleaf AL, Marto JA, Geyer M, Bullock AN, Young RA, Gray NS. Zhang T, et al. Among authors: bullock an. Nat Chem Biol. 2016 Oct;12(10):876-84. doi: 10.1038/nchembio.2166. Epub 2016 Aug 29. Nat Chem Biol. 2016. PMID: 27571479 Free PMC article.
Targeting RIPK1,2,3 to combat inflammation.
Bullock AN, Degterev A. Bullock AN, et al. Oncotarget. 2015 Oct 27;6(33):34057-8. doi: 10.18632/oncotarget.6106. Oncotarget. 2015. PMID: 26472031 Free PMC article. No abstract available.
Target 2035 - update on the quest for a probe for every protein.
Müller S, Ackloo S, Al Chawaf A, Al-Lazikani B, Antolin A, Baell JB, Beck H, Beedie S, Betz UAK, Bezerra GA, Brennan PE, Brown D, Brown PJ, Bullock AN, Carter AJ, Chaikuad A, Chaineau M, Ciulli A, Collins I, Dreher J, Drewry D, Edfeldt K, Edwards AM, Egner U, Frye SV, Fuchs SM, Hall MD, Hartung IV, Hillisch A, Hitchcock SH, Homan E, Kannan N, Kiefer JR, Knapp S, Kostic M, Kubicek S, Leach AR, Lindemann S, Marsden BD, Matsui H, Meier JL, Merk D, Michel M, Morgan MR, Mueller-Fahrnow A, Owen DR, Perry BG, Rosenberg SH, Saikatendu KS, Schapira M, Scholten C, Sharma S, Simeonov A, Sundström M, Superti-Furga G, Todd MH, Tredup C, Vedadi M, von Delft F, Willson TM, Winter GE, Workman P, Arrowsmith CH. Müller S, et al. Among authors: bullock an. RSC Med Chem. 2021 Dec 3;13(1):13-21. doi: 10.1039/d1md00228g. eCollection 2022 Jan 27. RSC Med Chem. 2021. PMID: 35211674 Free PMC article.
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective.
Ong HW, Liang Y, Richardson W, Lowry ER, Wells CI, Chen X, Silvestre M, Dempster K, Silvaroli JA, Smith JL, Wichterle H, Pabla NS, Ultanir SK, Bullock AN, Drewry DH, Axtman AD. Ong HW, et al. Among authors: bullock an. ACS Chem Neurosci. 2023 May 3;14(9):1672-1685. doi: 10.1021/acschemneuro.3c00135. Epub 2023 Apr 21. ACS Chem Neurosci. 2023. PMID: 37084253 Free PMC article.
Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease.
Al-Shaibi AA, Abdel-Motal UM, Hubrack SZ, Bullock AN, Al-Marri AA, Agrebi N, Al-Subaiey AA, Ibrahim NA, Charles AK; COLORS in IBD-Qatar Study Group; Elawad M, Uhlig HH, Lo B. Al-Shaibi AA, et al. Among authors: bullock an. Cell Mol Gastroenterol Hepatol. 2021;12(5):1809-1830. doi: 10.1016/j.jcmgh.2021.07.001. Epub 2021 Jul 6. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34237462 Free PMC article.
Structural basis of Keap1 interactions with Nrf2.
Canning P, Sorrell FJ, Bullock AN. Canning P, et al. Among authors: bullock an. Free Radic Biol Med. 2015 Nov;88(Pt B):101-107. doi: 10.1016/j.freeradbiomed.2015.05.034. Epub 2015 Jun 7. Free Radic Biol Med. 2015. PMID: 26057936 Free PMC article. Review.
Discovery of Conformationally Constrained ALK2 Inhibitors.
González-Álvarez H, Ensan D, Xin T, Wong JF, Zepeda-Velázquez CA, Cros J, Sweeney MN, Hoffer L, Kiyota T, Wilson BJ, Aman A, Roberts O, Isaac MB, Bullock AN, Smil D, Al-Awar R. González-Álvarez H, et al. Among authors: bullock an. J Med Chem. 2024 Mar 28;67(6):4707-4725. doi: 10.1021/acs.jmedchem.3c02308. Epub 2024 Mar 18. J Med Chem. 2024. PMID: 38498998 Free PMC article.
103 results