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Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.
Neurobiol Dis. 2021 May;152:105289. doi: 10.1016/j.nbd.2021.105289. Epub 2021 Feb 10.
Neurobiol Dis. 2021.
PMID: 33577922
Free article.
In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism.
Sen NE, Arsovic A, Meierhofer D, Brodesser S, Oberschmidt C, Canet-Pons J, Kaya ZE, Halbach MV, Gispert S, Sandhoff K, Auburger G.
Sen NE, et al. Among authors: arsovic a.
Int J Mol Sci. 2019 Nov 21;20(23):5854. doi: 10.3390/ijms20235854.
Int J Mol Sci. 2019.
PMID: 31766565
Free PMC article.
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Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation.
Sen NE, Canet-Pons J, Halbach MV, Arsovic A, Pilatus U, Chae WH, Kaya ZE, Seidel K, Rollmann E, Mittelbronn M, Meierhofer D, De Zeeuw CI, Bosman LWJ, Gispert S, Auburger G.
Sen NE, et al. Among authors: arsovic a.
Neurobiol Dis. 2019 Dec;132:104559. doi: 10.1016/j.nbd.2019.104559. Epub 2019 Jul 31.
Neurobiol Dis. 2019.
PMID: 31376479
Free article.
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Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule-Purkinje Neuron Synaptic Strength.
Arsović A, Halbach MV, Canet-Pons J, Esen-Sehir D, Döring C, Freudenberg F, Czechowska N, Seidel K, Baader SL, Gispert S, Sen NE, Auburger G.
Arsović A, et al.
Int J Mol Sci. 2020 Sep 12;21(18):6673. doi: 10.3390/ijms21186673.
Int J Mol Sci. 2020.
PMID: 32932600
Free PMC article.
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Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence.
Key J, Sen NE, Arsović A, Krämer S, Hülse R, Khan NN, Meierhofer D, Gispert S, Koepf G, Auburger G.
Key J, et al. Among authors: arsovic a.
Cells. 2020 Oct 2;9(10):2229. doi: 10.3390/cells9102229.
Cells. 2020.
PMID: 33023155
Free PMC article.
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