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Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis.
Yamamoto-Imoto H, Minami S, Shioda T, Yamashita Y, Sakai S, Maeda S, Yamamoto T, Oki S, Takashima M, Yamamuro T, Yanagawa K, Edahiro R, Iwatani M, So M, Tokumura A, Abe T, Imamura R, Nonomura N, Okada Y, Ayer DE, Ogawa H, Hara E, Takabatake Y, Isaka Y, Nakamura S, Yoshimori T. Yamamoto-Imoto H, et al. Cell Rep. 2022 Mar 1;38(9):110444. doi: 10.1016/j.celrep.2022.110444. Cell Rep. 2022. PMID: 35235784 Free article.
Furthermore, we find that MondoA knockout mice have exacerbated senescence during ischemic acute kidney injury (AKI), and a decrease of MondoA in the nucleus is correlated with human aging and ischemic AKI. ...
Furthermore, we find that MondoA knockout mice have exacerbated senescence during ischemic acute kidney injury (AKI), and a decrease …
Non-recovery of vancomycin-associated nephrotoxicity is related to worsening survival outcomes: Combined retrospective analyses of two real-world databases.
Chuma M, Hamano H, Bando T, Kondo M, Okada N, Izumi Y, Ishida S, Yoshioka T, Asada M, Niimura T, Zamami Y, Takechi K, Goda M, Miyata K, Yagi K, Kasamo S, Izawa-Ishizawa Y, Azuma M, Yanagawa H, Tasaki Y, Ishizawa K. Chuma M, et al. Basic Clin Pharmacol Toxicol. 2022 Dec;131(6):525-535. doi: 10.1111/bcpt.13799. Epub 2022 Oct 7. Basic Clin Pharmacol Toxicol. 2022. PMID: 36169161 Free article.
The HR for VAN recovery was lower for patients with acute kidney injury (AKI) stage 2 (HR: 0.09; 95% CI: 0.02-0.40). Thus, worsening survival outcomes were associated with non-recovery of VAN, whereby AKI stage 2 was a significant risk factor. ...
The HR for VAN recovery was lower for patients with acute kidney injury (AKI) stage 2 (HR: 0.09; 95% CI: 0.02-0.40). Thus, worsening …
Effects and cost of glycyrrhizin in the treatment of upper respiratory tract infections in members of the Japanese maritime self-defense force: Preliminary report of a prospective, randomized, double-blind, controlled, parallel-group, alternate-day treatment assignment clinical trial.
Yanagawa Y, Ogura M, Fujimoto E, Shono S, Okuda E. Yanagawa Y, et al. Curr Ther Res Clin Exp. 2004 Jan;65(1):26-33. doi: 10.1016/S0011-393X(04)90002-1. Curr Ther Res Clin Exp. 2004. PMID: 24936101 Free PMC article.