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Year Number of Results
2009 1
2010 2
2011 2
2012 1
2013 1
2014 4
2015 5
2016 2
2017 3
2018 1
2019 2
2020 1
2021 4
2022 3
2023 3
2024 1

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29 results

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Page 1
Frentizole derivatives with mTOR inhibiting and senomorphic properties.
Chrienova Z, Rysanek D, Novak J, Vasicova P, Oleksak P, Andrys R, Skarka A, Dumanovic J, Milovanovic Z, Jacevic V, Chvojkova M, Holubova K, Vales K, Skoupilova V, Valko M, Jomova K, Alomar SY, Botelho FD, Franca TCC, Kuca K, Hodny Z, Nepovimova E. Chrienova Z, et al. Among authors: skarka a. Biomed Pharmacother. 2023 Nov;167:115600. doi: 10.1016/j.biopha.2023.115600. Epub 2023 Sep 30. Biomed Pharmacother. 2023. PMID: 37783152 Free article.
Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation.
Benek O, Vaskova M, Miskerikova M, Schmidt M, Andrys R, Rotterova A, Skarka A, Hatlapatkova J, Karasova JZ, Medvecky M, Hroch L, Vinklarova L, Fisar Z, Hroudova J, Handl J, Capek J, Rousar T, Kobrlova T, Dolezal R, Soukup O, Aitken L, Gunn-Moore F, Musilek K. Benek O, et al. Among authors: skarka a. Eur J Med Chem. 2023 Oct 5;258:115593. doi: 10.1016/j.ejmech.2023.115593. Epub 2023 Jun 24. Eur J Med Chem. 2023. PMID: 37390508
Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics.
Chrienova Z, Rysanek D, Oleksak P, Stary D, Bajda M, Reinis M, Mikyskova R, Novotny O, Andrys R, Skarka A, Vasicova P, Novak J, Valis M, Kuca K, Hodny Z, Nepovimova E. Chrienova Z, et al. Among authors: skarka a. Front Aging Neurosci. 2022 Dec 6;14:1048260. doi: 10.3389/fnagi.2022.1048260. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36561137 Free PMC article.
BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS.
Prchalova E, Sukupova M, Malinak D, Andrys R, Sivak L, Pekarik V, Skarka A, Svobodova J, Prchal L, Fresser L, Heger Z, Musilek K. Prchalova E, et al. Among authors: skarka a. Biomed Pharmacother. 2023 Nov;167:115490. doi: 10.1016/j.biopha.2023.115490. Epub 2023 Sep 16. Biomed Pharmacother. 2023. PMID: 37722189 Free article.
Isoquinoline alkaloids as a novel type of AKR1C3 inhibitors.
Skarydova L, Hofman J, Chlebek J, Havrankova J, Kosanova K, Skarka A, Hostalkova A, Plucha T, Cahlikova L, Wsol V. Skarydova L, et al. Among authors: skarka a. J Steroid Biochem Mol Biol. 2014 Sep;143:250-8. doi: 10.1016/j.jsbmb.2014.04.005. Epub 2014 Apr 24. J Steroid Biochem Mol Biol. 2014. PMID: 24769118
Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter.
Vagiannis D, Zhang Y, Budagaga Y, Novotna E, Skarka A, Kammerer S, Küpper JH, Hofman J. Vagiannis D, et al. Among authors: skarka a. Toxicol Appl Pharmacol. 2022 Jan 1;434:115823. doi: 10.1016/j.taap.2021.115823. Epub 2021 Dec 9. Toxicol Appl Pharmacol. 2022. PMID: 34896433
Human DHRS7, promising enzyme in metabolism of steroids and retinoids?
Štambergová H, Zemanová L, Lundová T, Malčeková B, Skarka A, Šafr M, Wsól V. Štambergová H, et al. Among authors: skarka a. J Steroid Biochem Mol Biol. 2016 Jan;155(Pt A):112-9. doi: 10.1016/j.jsbmb.2015.09.041. Epub 2015 Oct 22. J Steroid Biochem Mol Biol. 2016. PMID: 26466768
29 results