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Ciclopirox ethanolamine preserves the immature state of human HSCs by mediating intracellular iron content.
Talkhoncheh MS, Baudet A, Ek F, Subramaniam A, Kao YR, Miharada N, Karlsson C, Oburoglu L, Rydström A, Zemaitis K, Alattar AG, Rak J, Pietras K, Olsson R, Will B, Larsson J. Talkhoncheh MS, et al. Among authors: alattar ag. Blood Adv. 2023 Dec 26;7(24):7407-7417. doi: 10.1182/bloodadvances.2023009844. Blood Adv. 2023. PMID: 37487020 Free PMC article.
Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity.
Mattebo A, Sen T, Jassinskaja M, Pimková K, Prieto González-Albo I, Alattar AG, Ramakrishnan R, Lang S, Järås M, Hansson J, Soneji S, Singbrant S, van den Akker E, Flygare J. Mattebo A, et al. Among authors: alattar ag. Sci Rep. 2021 Aug 5;11(1):15898. doi: 10.1038/s41598-021-95291-1. Sci Rep. 2021. PMID: 34354145 Free PMC article.
Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype.
Thornton N, Karamatic Crew V, Tilley L, Green CA, Tay CL, Griffiths RE, Singleton BK, Spring F, Walser P, Alattar AG, Jones B, Laundy R, Storry JR, Möller M, Wall L, Charlewood R, Westhoff CM, Lomas-Francis C, Yahalom V, Feick U, Seltsam A, Mayer B, Olsson ML, Anstee DJ. Thornton N, et al. Among authors: alattar ag. Nat Commun. 2020 Jul 16;11(1):3569. doi: 10.1038/s41467-020-17060-4. Nat Commun. 2020. PMID: 32678083 Free PMC article.
Human radical scavenger α1-microglobulin protects against hemolysis in vitro and α1-microglobulin knockout mice exhibit a macrocytic anemia phenotype.
Kristiansson A, Bergwik J, Alattar AG, Flygare J, Gram M, Hansson SR, Olsson ML, Storry JR, Allhorn M, Åkerström B. Kristiansson A, et al. Among authors: alattar ag. Free Radic Biol Med. 2021 Jan;162:149-159. doi: 10.1016/j.freeradbiomed.2020.02.018. Epub 2020 Feb 21. Free Radic Biol Med. 2021. PMID: 32092412