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The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix-significance for protein elimination failure arteriopathies.
Sharp MM, Cassidy J, Thornton T, Lyles J, Keable A, Gatherer M, Yasui M, Abe Y, Shibata S, Weller RO, Górecki DC, Carare RO. Sharp MM, et al. Among authors: keable a. Acta Neuropathol Commun. 2021 Oct 21;9(1):171. doi: 10.1186/s40478-021-01274-8. Acta Neuropathol Commun. 2021. PMID: 34674769 Free PMC article.
Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia.
MacGregor Sharp M, Saito S, Keable A, Gatherer M, Aldea R, Agarwal N, Simpson JE, Wharton SB, Weller RO, Carare RO. MacGregor Sharp M, et al. Among authors: keable a. Acta Neuropathol Commun. 2020 Aug 8;8(1):131. doi: 10.1186/s40478-020-01009-1. Acta Neuropathol Commun. 2020. PMID: 32771063 Free PMC article.
Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy.
Keable A, Fenna K, Yuen HM, Johnston DA, Smyth NR, Smith C, Al-Shahi Salman R, Samarasekera N, Nicoll JA, Attems J, Kalaria RN, Weller RO, Carare RO. Keable A, et al. Biochim Biophys Acta. 2016 May;1862(5):1037-46. doi: 10.1016/j.bbadis.2015.08.024. Epub 2015 Aug 29. Biochim Biophys Acta. 2016. PMID: 26327684 Free PMC article.