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65 results

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Page 1
Focused ultrasound-mediated brain genome editing.
Lao YH, Ji R, Zhou JK, Snow KJ, Kwon N, Saville E, He S, Chauhan S, Chi CW, Datta MS, Zhang H, Quek CH, Cai SS, Li M, Gaitan Y, Bechtel L, Wu SY, Lutz CM, Tomer R, Murray SA, Chavez A, Konofagou EE, Leong KW. Lao YH, et al. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2302910120. doi: 10.1073/pnas.2302910120. Epub 2023 Aug 14. Proc Natl Acad Sci U S A. 2023. PMID: 37579143 Free PMC article.
SUMO protease SENP1 deSUMOylates and stabilizes c-Myc.
Sun XX, Chen Y, Su Y, Wang X, Chauhan KM, Liang J, Daniel CJ, Sears RC, Dai MS. Sun XX, et al. Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):10983-10988. doi: 10.1073/pnas.1802932115. Epub 2018 Oct 10. Proc Natl Acad Sci U S A. 2018. PMID: 30305424 Free PMC article.
Together, these results reveal that SENP1 is a crucial c-Myc deSUMOylating enzyme that positively regulates c-Myc's stability and activity....
Together, these results reveal that SENP1 is a crucial c-Myc deSUMOylating enzyme that positively regulates c-Myc's stability and act …
Optofluidic control of rodent learning using cloaked caged glutamate.
Durand-de Cuttoli R, Chauhan PS, Pétriz Reyes A, Faure P, Mourot A, Ellis-Davies GCR. Durand-de Cuttoli R, et al. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6831-6835. doi: 10.1073/pnas.1920869117. Epub 2020 Mar 9. Proc Natl Acad Sci U S A. 2020. PMID: 32152102 Free PMC article.
Exome sequencing efficacy and phenotypic expansions involving esophageal atresia/tracheoesophageal fistula plus.
Sy MR, Chauhan J, Prescott K, Imam A, Kraus A, Beleza A, Salkeld L, Hosdurga S, Parker M, Vasudevan P, Islam L, Goel H, Bain N, Park SM, Mohammed S, Dieterich K, Coutton C, Satre V, Vieville G, Donaldson A, Beneteau C, Ghoumid J, Van Den Bogaert K, Boogaerts A, Boudry E, Vanlerberghe C, Petit F, Bernardini L, Torres B, Mattina T, Carli D, Mandrile G, Pinelli M, Brunetti-Pierri N, Neas K, Beddow R, Tørring PM, Faletra F, Spedicati B, Gasparini P, Mussa A, Ferrero GB, Lampe A, Lam W, Bi W, Bacino CA, Kuwahara A, Bush JO, Zhao X, Luna PN, Shaw CA, Rosenfeld JA, Scott DA. Sy MR, et al. Am J Med Genet A. 2022 Dec;188(12):3492-3504. doi: 10.1002/ajmg.a.62976. Epub 2022 Sep 22. Am J Med Genet A. 2022. PMID: 36135330 Free PMC article.
The helicase-like transcription factor redirects the autophagic flux and restricts human T cell leukemia virus type 1 infection.
Beauvois A, Gazon H, Chauhan PS, Jamakhani M, Jacques JR, Thiry M, Dejardin E, Valentin ED, Twizere JC, Péloponèse JM, Njock MS, Yasunaga JI, Matsuoka M, Hamaïdia M, Willems L. Beauvois A, et al. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2216127120. doi: 10.1073/pnas.2216127120. Epub 2023 Jul 24. Proc Natl Acad Sci U S A. 2023. PMID: 37487091 Free PMC article.
Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Abeta oligomers.
Habashi M, Vutla S, Tripathi K, Senapati S, Chauhan PS, Haviv-Chesner A, Richman M, Mohand SA, Dumulon-Perreault V, Mulamreddy R, Okun E, Chill JH, Guérin B, Lubell WD, Rahimipour S. Habashi M, et al. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2210766119. doi: 10.1073/pnas.2210766119. Epub 2022 Nov 28. Proc Natl Acad Sci U S A. 2022. PMID: 36442093 Free PMC article.
Transient soluble oligomers of amyloid-beta (Abeta) are toxic and accumulate early prior to insoluble plaque formation and cognitive impairment in Alzheimer's disease (AD). Synthetic cyclic D,L-alpha-peptides (e.g., 1) self-assemble into cross beta-sheet nanotubes, react w …
Transient soluble oligomers of amyloid-beta (Abeta) are toxic and accumulate early prior to insoluble plaque formation and cognitive impairm …
65 results