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Using artificial intelligence methods to speed up drug discovery.
Álvarez-Machancoses Ó, Fernández-Martínez JL. Álvarez-Machancoses Ó, et al. Expert Opin Drug Discov. 2019 Aug;14(8):769-777. doi: 10.1080/17460441.2019.1621284. Epub 2019 May 29. Expert Opin Drug Discov. 2019. PMID: 31140873 Review.
On the Role of Artificial Intelligence in Genomics to Enhance Precision Medicine.
Álvarez-Machancoses Ó, DeAndrés Galiana EJ, Cernea A, Fernández de la Viña J, Fernández-Martínez JL. Álvarez-Machancoses Ó, et al. Pharmgenomics Pers Med. 2020 Mar 19;13:105-119. doi: 10.2147/PGPM.S205082. eCollection 2020. Pharmgenomics Pers Med. 2020. PMID: 32256101 Free PMC article. Review.
Analysis of transcriptomic responses to SARS-CoV-2 reveals plausible defective pathways responsible for increased susceptibility to infection and complications and helps to develop fast-track repositioning of drugs against COVID-19.
deAndrés-Galiana EJ, Fernández-Martínez JL, Álvarez-Machancoses Ó, Bea G, Galmarini CM, Kloczkowski A. deAndrés-Galiana EJ, et al. Among authors: alvarez machancoses o. Comput Biol Med. 2022 Oct;149:106029. doi: 10.1016/j.compbiomed.2022.106029. Epub 2022 Aug 30. Comput Biol Med. 2022. PMID: 36067633 Free PMC article.
Particle Swarm Optimization and Uncertainty Assessment in Inverse Problems.
Pallero JLG, Fernández-Muñiz MZ, Cernea A, Álvarez-Machancoses Ó, Pedruelo-González LM, Bonvalot S, Fernández-Martínez JL. Pallero JLG, et al. Among authors: alvarez machancoses o. Entropy (Basel). 2018 Jan 30;20(2):96. doi: 10.3390/e20020096. Entropy (Basel). 2018. PMID: 33265187 Free PMC article.