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Year Number of Results
2002 1
2003 2
2004 3
2005 2
2006 1
2007 2
2008 1
2009 3
2010 2
2011 1
2024 0

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18 results

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Page 1
The identification of orally bioavailable thrombopoietin agonists.
Munchhof MJ, Antipas AS, Blumberg LC, Brissette WH, Brown MF, Casavant JM, Doty JL, Driscoll J, Harris TM, Wolf-Gouveia LA, Jones CS, Li Q, Linde RG, Lira PD, Marfat A, McElroy E, Mitton-Fry M, McCurdy SP, Reiter LA, Ripp SL, Shavnya A, Thomasco LM, Trevena KA. Munchhof MJ, et al. Among authors: brissette wh. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1428-30. doi: 10.1016/j.bmcl.2009.01.032. Epub 2009 Jan 15. Bioorg Med Chem Lett. 2009. PMID: 19186055
Pyrimidine benzamide-based thrombopoietin receptor agonists.
Reiter LA, Subramanyam C, Mangual EJ, Jones CS, Smeets MI, Brissette WH, McCurdy SP, Lira PD, Linde RG, Li Q, Zhang F, Antipas AS, Blumberg LC, Doty JL, Driscoll JP, Munchhof MJ, Ripp SL, Shavnya A, Shepard RM, Sperger D, Thomasco LM, Trevena KA, Wolf-Gouveia LA, Zhang L. Reiter LA, et al. Among authors: brissette wh. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5447-54. doi: 10.1016/j.bmcl.2007.07.038. Epub 2007 Jul 31. Bioorg Med Chem Lett. 2007. PMID: 17707640
Potent small molecule CCR1 antagonists.
Kath JC, Brissette WH, Brown MF, Conklyn M, DiRico AP, Dorff P, Gladue RP, Lillie BM, Lira PD, Mairs EN, Martin WH, McElroy EB, McGlynn MA, Paradis TJ, Poss CS, Stock IA, Tylaska LA, Zheng D. Kath JC, et al. Among authors: brissette wh. Bioorg Med Chem Lett. 2004 May 3;14(9):2169-73. doi: 10.1016/j.bmcl.2004.02.021. Bioorg Med Chem Lett. 2004. PMID: 15081002
Analysis of the role of the HIF hydroxylase family members in erythropoiesis.
Fisher TS, Lira PD, Stock JL, Perregaux DG, Brissette WH, Ozolins TR, Li B. Fisher TS, et al. Among authors: brissette wh. Biochem Biophys Res Commun. 2009 Oct 30;388(4):683-8. doi: 10.1016/j.bbrc.2009.08.058. Epub 2009 Aug 14. Biochem Biophys Res Commun. 2009. PMID: 19683512
Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor.
Changelian PS, Flanagan ME, Ball DJ, Kent CR, Magnuson KS, Martin WH, Rizzuti BJ, Sawyer PS, Perry BD, Brissette WH, McCurdy SP, Kudlacz EM, Conklyn MJ, Elliott EA, Koslov ER, Fisher MB, Strelevitz TJ, Yoon K, Whipple DA, Sun J, Munchhof MJ, Doty JL, Casavant JM, Blumenkopf TA, Hines M, Brown MF, Lillie BM, Subramanyam C, Shang-Poa C, Milici AJ, Beckius GE, Moyer JD, Su C, Woodworth TG, Gaweco AS, Beals CR, Littman BH, Fisher DA, Smith JF, Zagouras P, Magna HA, Saltarelli MJ, Johnson KS, Nelms LF, Des Etages SG, Hayes LS, Kawabata TT, Finco-Kent D, Baker DL, Larson M, Si MS, Paniagua R, Higgins J, Holm B, Reitz B, Zhou YJ, Morris RE, O'Shea JJ, Borie DC. Changelian PS, et al. Among authors: brissette wh. Science. 2003 Oct 31;302(5646):875-8. doi: 10.1126/science.1087061. Science. 2003. PMID: 14593182
Destabilizing role of cathepsin S in murine atherosclerotic plaques.
Rodgers KJ, Watkins DJ, Miller AL, Chan PY, Karanam S, Brissette WH, Long CJ, Jackson CL. Rodgers KJ, et al. Among authors: brissette wh. Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):851-6. doi: 10.1161/01.ATV.0000203526.75772.4b. Epub 2006 Jan 12. Arterioscler Thromb Vasc Biol. 2006. PMID: 16410454
Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection.
Flanagan ME, Blumenkopf TA, Brissette WH, Brown MF, Casavant JM, Shang-Poa C, Doty JL, Elliott EA, Fisher MB, Hines M, Kent C, Kudlacz EM, Lillie BM, Magnuson KS, McCurdy SP, Munchhof MJ, Perry BD, Sawyer PS, Strelevitz TJ, Subramanyam C, Sun J, Whipple DA, Changelian PS. Flanagan ME, et al. Among authors: brissette wh. J Med Chem. 2010 Dec 23;53(24):8468-84. doi: 10.1021/jm1004286. Epub 2010 Nov 24. J Med Chem. 2010. PMID: 21105711
Novel CCR1 antagonists with improved metabolic stability.
Brown MF, Avery M, Brissette WH, Chang JH, Colizza K, Conklyn M, DiRico AP, Gladue RP, Kath JC, Krueger SS, Lira PD, Lillie BM, Lundquist GD, Mairs EN, McElroy EB, McGlynn MA, Paradis TJ, Poss CS, Rossulek MI, Shepard RM, Sims J, Strelevitz TJ, Truesdell S, Tylaska LA, Yoon K, Zheng D. Brown MF, et al. Among authors: brissette wh. Bioorg Med Chem Lett. 2004 May 3;14(9):2175-9. doi: 10.1016/j.bmcl.2004.02.022. Bioorg Med Chem Lett. 2004. PMID: 15081003
18 results