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2004 1
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84 results

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Page 1
Development and Evaluation of 1'-Acetoxychavicol Acetate (ACA)-Loaded Nanostructured Lipid Carriers for Prostate Cancer Therapy.
Subramaniam B, Arshad NM, Malagobadan S, Misran M, Nyamathulla S, Mun KS, Nagoor NH. Subramaniam B, et al. Pharmaceutics. 2021 Mar 24;13(4):439. doi: 10.3390/pharmaceutics13040439. Pharmaceutics. 2021. PMID: 33804975 Free PMC article.
1'-acetoxychavicol acetate (ACA) extracted from the rhizomes of Alpinia conchigera Griff (Zingiberaceae) has been shown to deregulate the NF-qB signaling pathway and induce apoptosis-mediated cell death in many cancer types. However, ACA is a hydrophobic ester
1'-acetoxychavicol acetate (ACA) extracted from the rhizomes of Alpinia conchigera Griff (Zingiberaceae) has been shown to deregulate …
Palmitic acid methyl ester is a novel neuroprotective agent against cardiac arrest.
Lee RH, Couto E Silva A, Possoit HE, Lerner FM, Chen PY, Azizbayeva R, Citadin CT, Wu CY, Neumann JT, Lin HW. Lee RH, et al. Prostaglandins Leukot Essent Fatty Acids. 2019 Aug;147:6-14. doi: 10.1016/j.plefa.2018.11.011. Epub 2018 Nov 23. Prostaglandins Leukot Essent Fatty Acids. 2019. PMID: 30514597 Free PMC article.
Additionally, functional learning and spatial memory assessments (via T-maze) 3 days after asphyxial cardiac arrest (ACA) suggest that PAME-treated rats have improved learning and memory recovery versus ACA alone. Furthermore, improved neuronal survival in the CA1 r …
Additionally, functional learning and spatial memory assessments (via T-maze) 3 days after asphyxial cardiac arrest (ACA) suggest tha …
Stearic acid methyl ester affords neuroprotection and improves functional outcomes after cardiac arrest.
Chen PY, Wu CY, Clemons GA, Citadin CT, Couto E Silva A, Possoit HE, Azizbayeva R, Forren NE, Liu CH, Rao KNS, Krzywanski DM, Lee RH, Neumann JT, Lin HW. Chen PY, et al. Prostaglandins Leukot Essent Fatty Acids. 2020 Aug;159:102138. doi: 10.1016/j.plefa.2020.102138. Epub 2020 May 23. Prostaglandins Leukot Essent Fatty Acids. 2020. PMID: 32663656
We previously identified a saturated fatty acid (stearic acid methyl ester, SAME) that was released from the superior cervical ganglion (sympathetic ganglion). The function of stearic acid methyl ester is currently unknown. Here, we show that SAME can inhibit the de …
We previously identified a saturated fatty acid (stearic acid methyl ester, SAME) that was released from the superior cervical gangli …
Palmitic acid methyl ester inhibits cardiac arrest-induced neuroinflammation and mitochondrial dysfunction.
Wu CY, Couto E Silva A, Citadin CT, Clemons GA, Acosta CH, Knox BA, Grames MS, Rodgers KM, Lee RH, Lin HW. Wu CY, et al. Prostaglandins Leukot Essent Fatty Acids. 2021 Feb;165:102227. doi: 10.1016/j.plefa.2020.102227. Epub 2020 Dec 17. Prostaglandins Leukot Essent Fatty Acids. 2021. PMID: 33445063 Free PMC article.
We previously discovered that palmitic acid methyl ester (PAME) is a potent vasodilator released from the sympathetic ganglion with vasoactive properties. ...Altogether, our findings suggest that PAME can provide neuroprotection in the presence of ACA to alleviate n …
We previously discovered that palmitic acid methyl ester (PAME) is a potent vasodilator released from the sympathetic ganglion with v …
Steroid-linked nitrogen mustards as potential anticancer therapeutics: a review.
Saha P, Debnath C, Bérubé G. Saha P, et al. J Steroid Biochem Mol Biol. 2013 Sep;137:271-300. doi: 10.1016/j.jsbmb.2013.05.004. Epub 2013 May 18. J Steroid Biochem Mol Biol. 2013. PMID: 23692738 Review.
Among these compounds, modified steroids with aromatic nitrogen mustards linked by an ester function were found to have better DNA alkylating properties, improved selectivity as well as low toxicity. ...
Among these compounds, modified steroids with aromatic nitrogen mustards linked by an ester function were found to have better DNA al …
Cancer-preventive anti-oxidants that attenuate free radical generation by inflammatory cells.
Murakami A, Ohigashi H. Murakami A, et al. Biol Chem. 2006 Apr;387(4):387-92. doi: 10.1515/BC.2006.052. Biol Chem. 2006. PMID: 16606336 Review.
We have recently established novel bioassay systems, in which either phorbol ester-stimulated, differentiated HL-60 human leukemia cells or lipopolysaccharide (LPS)-stimulated RAW264.7 murine macrophages were co-cultured with AS52 Chinese hamster ovary cells. Extensive scr …
We have recently established novel bioassay systems, in which either phorbol ester-stimulated, differentiated HL-60 human leukemia ce …
Environmentally adapted bio-oil compounds-derived polyolesters synthesis: Optimization and properties of base fluids.
Cheryl-Low YL, Kong PS, Lee HV. Cheryl-Low YL, et al. J Hazard Mater. 2021 Apr 5;407:124365. doi: 10.1016/j.jhazmat.2020.124365. Epub 2020 Oct 27. J Hazard Mater. 2021. PMID: 33162238
Non-edible bio-oil derived from lignocellulosic biomass could be used as environmentally friendly lubricant-ester base stock for maritime and road-type transportations. However, the use of crude bio-oil with highly oxygenated compounds required further upgrading to yield …
Non-edible bio-oil derived from lignocellulosic biomass could be used as environmentally friendly lubricant-ester base stock for mari …
Development of an RNA-protein crosslinker to capture protein interactions with diverse RNA structures in cells.
Han Y, Guo X, Zhang T, Wang J, Ye K. Han Y, et al. RNA. 2022 Mar;28(3):390-399. doi: 10.1261/rna.078896.121. Epub 2021 Dec 16. RNA. 2022. PMID: 34916333 Free PMC article.
Here, we report the development of an RNA-protein crosslinker (AMT-NHS) composed of a psoralen derivative and an N-hydroxysuccinimide ester group, which react with RNA bases and primary amines of protein, respectively. We show that AMT-NHS can penetrate into living yeast c …
Here, we report the development of an RNA-protein crosslinker (AMT-NHS) composed of a psoralen derivative and an N-hydroxysuccinimide est
Biochemical characterization of an acetylesterase from Bacillus subtilis and its application for 7-aminocephalosporanic acid deacetylation.
Wang X, Nong S, Li J, Liu Y, Wu Q, Huang Z, Xu B, Ding J. Wang X, et al. Front Microbiol. 2023 May 3;14:1164815. doi: 10.3389/fmicb.2023.1164815. eCollection 2023. Front Microbiol. 2023. PMID: 37206334 Free PMC article.
Enzymes involved in the conversion from 7-ACA to D-7-ACA present critical resources in the pharmaceutical industry. ...This study provided a promising 7-ACA deacetylase candidate that could be applied to produce D-7-ACA from 7-ACA in the pharmac …
Enzymes involved in the conversion from 7-ACA to D-7-ACA present critical resources in the pharmaceutical industry. ...This st …
84 results