Brown KD - Search Results

1

Multiple ATM-dependent pathways: an explanation for pleiotropy.

Brown KD, Barlow C, Wynshaw-Boris A. Brown KD, et al. Am J Hum Genet. 1999 Jan;64(1):46-50. doi: 10.1086/302223. Am J Hum Genet. 1999. PMID: 9915942 Free PMC article. Review. No abstract available.

2

Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways.

Barlow C, Brown KD, Deng CX, Tagle DA, Wynshaw-Boris A. Barlow C, et al. Among authors: brown kd. Nat Genet. 1997 Dec;17(4):453-6. doi: 10.1038/ng1297-453. Nat Genet. 1997. PMID: 9398849

3

ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation.

Barlow C, Ribaut-Barassin C, Zwingman TA, Pope AJ, Brown KD, Owens JW, Larson D, Harrington EA, Haeberle AM, Mariani J, Eckhaus M, Herrup K, Bailly Y, Wynshaw-Boris A. Barlow C, et al. Among authors: brown kd. Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):871-6. doi: 10.1073/pnas.97.2.871. Proc Natl Acad Sci U S A. 2000. PMID: 10639172 Free PMC article.

4

Ataxia telangiectasia mutated is essential during adult neurogenesis.

Allen DM, van Praag H, Ray J, Weaver Z, Winrow CJ, Carter TA, Braquet R, Harrington E, Ried T, Brown KD, Gage FH, Barlow C. Allen DM, et al. Among authors: brown kd. Genes Dev. 2001 Mar 1;15(5):554-66. doi: 10.1101/gad.869001. Genes Dev. 2001. PMID: 11238376 Free PMC article.

5

Regulation of DNA-dependent protein kinase activity by ionizing radiation-activated abl kinase is an ATM-dependent process.

Shangary S, Brown KD, Adamson AW, Edmonson S, Ng B, Pandita TK, Yalowich J, Taccioli GE, Baskaran R. Shangary S, et al. Among authors: brown kd. J Biol Chem. 2000 Sep 29;275(39):30163-8. doi: 10.1074/jbc.M004302200. J Biol Chem. 2000. PMID: 10906134 Free article.

6

The mismatch repair system is required for S-phase checkpoint activation.

Brown KD, Rathi A, Kamath R, Beardsley DI, Zhan Q, Mannino JL, Baskaran R. Brown KD, et al. Nat Genet. 2003 Jan;33(1):80-4. doi: 10.1038/ng1052. Epub 2002 Nov 25. Nat Genet. 2003. PMID: 12447371

7

MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine.

Kim WJ, Rajasekaran B, Brown KD. Kim WJ, et al. Among authors: brown kd. J Biol Chem. 2007 Nov 2;282(44):32021-31. doi: 10.1074/jbc.M701451200. Epub 2007 Sep 5. J Biol Chem. 2007. PMID: 17804421 Free article.

8

The ATM/p53 pathway is commonly targeted for inactivation in squamous cell carcinoma of the head and neck (SCCHN) by multiple molecular mechanisms.

Bolt J, Vo QN, Kim WJ, McWhorter AJ, Thomson J, Hagensee ME, Friedlander P, Brown KD, Gilbert J. Bolt J, et al. Among authors: brown kd. Oral Oncol. 2005 Nov;41(10):1013-20. doi: 10.1016/j.oraloncology.2005.06.003. Epub 2005 Aug 31. Oral Oncol. 2005. PMID: 16139561

9

Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery.

Ha K, Lee GE, Palii SS, Brown KD, Takeda Y, Liu K, Bhalla KN, Robertson KD. Ha K, et al. Among authors: brown kd. Hum Mol Genet. 2011 Jan 1;20(1):126-40. doi: 10.1093/hmg/ddq451. Epub 2010 Oct 11. Hum Mol Genet. 2011. PMID: 20940144 Free PMC article.

10

Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line.

Kim WJ, Vo QN, Shrivastav M, Lataxes TA, Brown KD. Kim WJ, et al. Among authors: brown kd. Oncogene. 2002 May 30;21(24):3864-71. doi: 10.1038/sj.onc.1205485. Oncogene. 2002. PMID: 12032824

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