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Creation of human tumour cells with defined genetic elements.
Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, Weinberg RA. Hahn WC, et al. Among authors: beijersbergen rl. Nature. 1999 Jul 29;400(6743):464-8. doi: 10.1038/22780. Nature. 1999. PMID: 10440377
Inhibition of telomerase limits the growth of human cancer cells.
Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersbergen RL, Knoll JH, Meyerson M, Weinberg RA. Hahn WC, et al. Among authors: beijersbergen rl. Nat Med. 1999 Oct;5(10):1164-70. doi: 10.1038/13495. Nat Med. 1999. PMID: 10502820
Methylation of the human telomerase gene CpG island.
Dessain SK, Yu H, Reddel RR, Beijersbergen RL, Weinberg RA. Dessain SK, et al. Among authors: beijersbergen rl. Cancer Res. 2000 Feb 1;60(3):537-41. Cancer Res. 2000. PMID: 10676632
Telomerase-independent regulation of ATR by human telomerase RNA.
Kedde M, le Sage C, Duursma A, Zlotorynski E, van Leeuwen B, Nijkamp W, Beijersbergen R, Agami R. Kedde M, et al. J Biol Chem. 2006 Dec 29;281(52):40503-14. doi: 10.1074/jbc.M607676200. Epub 2006 Nov 10. J Biol Chem. 2006. PMID: 17098743 Free article.
EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis.
Heeg S, Hirt N, Queisser A, Schmieg H, Thaler M, Kunert H, Quante M, Goessel G, von Werder A, Harder J, Beijersbergen R, Blum HE, Nakagawa H, Opitz OG. Heeg S, et al. Cancer Sci. 2011 Feb;102(2):351-60. doi: 10.1111/j.1349-7006.2010.01796.x. Epub 2010 Dec 12. Cancer Sci. 2011. PMID: 21156006 Free article.
Mammalian life depends on two distinct pathways of DNA damage tolerance.
Buoninfante OA, Pilzecker B, Spanjaard A, de Groot D, Prekovic S, Song JY, Lieftink C, Ayidah M, Pritchard CEJ, Vivié J, Mcgrath KE, Huijbers IJ, Philipsen S, von Lindern M, Zwart W, Beijersbergen RL, Palis J, van den Berk PCM, Jacobs H. Buoninfante OA, et al. Among authors: beijersbergen rl. Proc Natl Acad Sci U S A. 2023 Jan 24;120(4):e2216055120. doi: 10.1073/pnas.2216055120. Epub 2023 Jan 20. Proc Natl Acad Sci U S A. 2023. PMID: 36669105 Free PMC article.
123 results