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A mutation in human immunodeficiency virus type 1 protease at position 88, located outside the active site, confers resistance to the hydroxyethylurea inhibitor SC-55389A.
Smidt ML, Potts KE, Tucker SP, Blystone L, Stiebel TR Jr, Stallings WC, McDonald JJ, Pillay D, Richman DD, Bryant ML. Smidt ML, et al. Among authors: tucker sp. Antimicrob Agents Chemother. 1997 Mar;41(3):515-22. doi: 10.1128/AAC.41.3.515. Antimicrob Agents Chemother. 1997. PMID: 9055985 Free PMC article.
Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen.
Macdonald SJ, Watson KG, Cameron R, Chalmers DK, Demaine DA, Fenton RJ, Gower D, Hamblin JN, Hamilton S, Hart GJ, Inglis GG, Jin B, Jones HT, McConnell DB, Mason AM, Nguyen V, Owens IJ, Parry N, Reece PA, Shanahan SE, Smith D, Wu WY, Tucker SP. Macdonald SJ, et al. Among authors: tucker sp. Antimicrob Agents Chemother. 2004 Dec;48(12):4542-9. doi: 10.1128/AAC.48.12.4542-4549.2004. Antimicrob Agents Chemother. 2004. PMID: 15561823 Free PMC article.
Structural characterization of respiratory syncytial virus fusion inhibitor escape mutants: homology model of the F protein and a syncytium formation assay.
Morton CJ, Cameron R, Lawrence LJ, Lin B, Lowe M, Luttick A, Mason A, McKimm-Breschkin J, Parker MW, Ryan J, Smout M, Sullivan J, Tucker SP, Young PR. Morton CJ, et al. Among authors: tucker sp. Virology. 2003 Jul 5;311(2):275-88. doi: 10.1016/s0042-6822(03)00115-6. Virology. 2003. PMID: 12842618 Free article.
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